First-pass extracted concept

CRISPR system

Candidate: toolkit item1 source documents3 linked claims

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Evidence Snippets

The CRISPR system has surged at the forefront of genome engineering tools in the field of RNA modulation.

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1review2017Molecular Medicine ReportsDOI PubMed

1 evidence snippet 3 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1application scopesupports2017Source 1DOI PubMed

This review describes CRISPR-system applications in RNA sequence manipulation, visualization of chromosomal loci in living cells, and modulation of transcription.

Quoted textsource-backed

we discuss some exciting applications of the CRISPR system, including the manipulation of RNA sequences, the visualization of chromosomal loci in living cells and the modulation of transcription

Claim 2performance summarysupports2017Source 1DOI PubMed

The review states that the CRISPR system is reliable and specific for altering gene expression when leveraging catalytically dead Cas9.

Quoted textsource-backed

The CRISPR system has been documented to be very reliable and specific in altering gene expression, via leveraging inactive catalytically dead CRISPR-associated protein 9 (Cas9).

Claim 3research utilitysupports2017Source 1DOI PubMed

The review presents the CRISPR system as a tool for analysis of gene regulation, loci mapping, and complex pathways.

Quoted textsource-backed

the CRISPR system is presented as an eminent tool for the meticulous analysis of gene regulation, loci mapping and complex pathways