First-pass extracted concept

Early heading date 4

Candidate: toolkit item1 source documents10 linked claims
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Aliases

Ehd4

Evidence Snippets

Here, we report isolation and characterization of a positive regulator of Ehd1, Early heading date 4 (Ehd4).
Evidence 1Source 1DOIPubMedprovenance

Supporting Sources

Linked Claims

Claim 1evolutionary conservationsupports2013Source 1DOIPubMed

Ehd4 is highly conserved in the Oryza genus including wild and cultivated rice and has no homologs in other species.

Quoted textsource-backed
Ehd4 is highly conserved in the Oryza genus including wild and cultivated rice, but has no homologs in other species
Claim 2expression patternsupports2013Source 1DOIPubMed

Ehd4 expression is most active in young leaves and shows a diurnal expression pattern similar to Ehd1 under both short-day and long-day conditions.

Quoted textsource-backed
Ehd4 expression is most active in young leaves with a diurnal expression pattern similar to that of Ehd1 under both short-day and long-day conditions.
Claim 3functional importancesupports2013Source 1DOIPubMed

Ehd4 is a novel Oryza-genus-specific regulator of Ehd1 that plays an essential role in photoperiodic control of flowering time in rice.

Quoted textsource-backed
We conclude that Ehd4 is a novel Oryza-genus-specific regulator of Ehd1, and it plays an essential role in photoperiodic control of flowering time in rice.
Claim 4gene regulationsupports2013Source 1DOIPubMed

Ehd4 up-regulates Hd3a and RFT1 expression through Ehd1.

Quoted textsource-backed
We show that Ehd4 up-regulates the expression of the "florigen" genes Hd3a and RFT1 through Ehd1
Claim 5molecular activitysupports2013Source 1DOIPubMed

Ehd4 binds nucleic acids in vitro and transactivates transcription in yeast, suggesting it functions as a transcriptional regulator.

Quoted textsource-backed
is able to bind to nucleic acids in vitro and transactivate transcription in yeast, suggesting that it likely functions as a transcriptional regulator
Claim 6molecular identitysupports2013Source 1DOIPubMed

Ehd4 encodes a novel CCCH-type zinc finger protein.

Quoted textsource-backed
Map-based cloning revealed that Ehd4 encodes a novel CCCH-type zinc finger protein
Claim 7mutant phenotypesupports2013Source 1DOIPubMed

ehd4 mutants show a never flowering phenotype under natural long-day conditions.

Quoted textsource-backed
ehd4 mutants showed a never flowering phenotype under natural long-day conditions.
Claim 8pathway independencesupports2013Source 1DOIPubMed

Ehd4 acts independently of other known Ehd1 regulators.

Quoted textsource-backed
but it acts independently of other known Ehd1 regulators
Claim 9regulatory rolesupports2013Source 1DOIPubMed

Ehd4 is a positive regulator of Ehd1.

Quoted textsource-backed
Here, we report isolation and characterization of a positive regulator of Ehd1, Early heading date 4 (Ehd4).
Claim 10subcellular localizationsupports2013Source 1DOIPubMed

Ehd4 is localized to the nucleus.

Quoted textsource-backed
which is localized to the nucleus