First-pass extracted concept

genetically-encoded Zn2+ sensors

Candidate: toolkit item1 source documents3 linked claims
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Aliases

targeted Zn2+ biosensors

Evidence Snippets

Screening with this instrument reveals increased heterogeneity in an array of targeted Zn2+ biosensors in HeLa cells... Subsequently, the instrument is used to screen and assess diversity in a number of HeLa-cell based genetic linker libraries for a family of genetically-encoded Zn2+ sensors.
Evidence 1Source 1provenance

Supporting Sources

Linked Claims

Claim 1characterization usesupports2017Source 1

Time-resolved fluorescence techniques were used to characterize the sensors and advance deeper molecular understanding to guide further development.

Quoted textsource-backed
Progress on sensor characterization is made using time-resolved fluorescence techniques to advance a deeper molecular understanding of these sensors to guide further development.
Claim 2library screening usesupports2017Source 1

The droplet microfluidic instrument was used to screen and assess diversity in HeLa-cell based genetic linker libraries for a family of genetically-encoded Zn2+ sensors.

Quoted textsource-backed
Subsequently, the instrument is used to screen and assess diversity in a number of HeLa-cell based genetic linker libraries for a family of genetically-encoded Zn2+ sensors.
Claim 3screening observationsupports2017Source 1

Screening with the droplet microfluidic instrument revealed increased heterogeneity among targeted Zn2+ biosensors in HeLa cells.

Quoted textsource-backed
Screening with this instrument reveals increased heterogeneity in an array of targeted Zn2+ biosensorsin HeLa cells that helps shed light on the complexities of these sensors in different chemical environments.