First-pass extracted concept

HY5 HOMOLOG

Candidate: toolkit item1 source documents7 linked claims
Live refresh every 5sNext refresh in 5s

Aliases

HYH

Evidence Snippets

the bZIP transcription factor HY5 HOMOLOG (HYH)
Evidence 1Source 1DOIPubMedprovenance

Supporting Sources

Linked Claims

Claim 1biological effectsupports2008Source 1DOIPubMed

Light induces peroxisome proliferation in Arabidopsis seedlings.

Quoted textsource-backed
We provide evidence that light induces proliferation of peroxisomes in Arabidopsis seedlings
Claim 2direct target relationshipsupports2008Source 1DOIPubMed

PEX11b is a direct target of HYH.

Quoted textsource-backed
suggesting that the PEX11b gene is a direct target of HYH
Claim 3dna bindingsupports2008Source 1DOIPubMed

HYH binds to the promoter of PEX11b.

Quoted textsource-backed
The HYH protein is able to bind to the promoter of PEX11b
Claim 4mutant phenotypesupports2008Source 1DOIPubMed

phyA and hyh mutants exhibit reduced peroxisome abundance.

Quoted textsource-backed
the phyA and hyh mutants exhibit reduced peroxisome abundance
Claim 5pathway modelsupports2008Source 1DOIPubMed

HYH and PEX11b constitute a branch of the phyA-mediated light signaling cascade that promotes peroxisome proliferation during seedling photomorphogenesis.

Quoted textsource-backed
We conclude that HYH and PEX11b constitute a novel branch of the phyA-mediated light signaling cascade, which promotes peroxisome proliferation during seedling photomorphogenesis.
Claim 6required for upregulationsupports2008Source 1DOIPubMed

phytochrome A and HYH are required for the up-regulation of PEX11b in the light.

Quoted textsource-backed
The far-red light receptor phytochrome A (phyA) and the bZIP transcription factor HY5 HOMOLOG (HYH) are both required for the up-regulation of PEX11b in the light.
Claim 7rescuesupports2008Source 1DOIPubMed

Overexpression of PEX11b rescues the reduced peroxisome abundance phenotype in phyA and hyh mutants.

Quoted textsource-backed
a phenotype that can be rescued by overexpressing PEX11b in these plants