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First-pass extracted concept

improved light-induced dimer

Candidate: toolkit item1 source documents5 linked claims
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Aliases

engineered switch, iLID, light-induced dimer

Evidence Snippets

Engineering an improved light-induced dimer (iLID) for controlling the localization and activity of signaling proteins
Evidence 1Source 1DOIprovenance

Supporting Sources

Linked Claims

Claim 1application capabilitysupports2020Source 1DOI

The engineered switch can be used to initiate signaling pathways in a specific region of a cell.

Quoted textsource-backed
can be used to initiate signaling pathways in a specific region of a cell
Claim 2binding affinity changesupports2020Source 1DOI

The engineered switch has more than 50-fold change in binding affinity upon light stimulation.

Quoted textsource-backed
has more than 50-fold change in binding affinity upon light stimulation
Claim 3engineering resultsupports2020Source 1DOI

The authors developed and applied methods to identify mutations that improve the effectiveness of a light-induced dimer.

Quoted textsource-backed
Here, we develop and apply methods for identifying mutations that improve the effectiveness of a light-induced dimer.
Claim 4modularitysupports2020Source 1DOI

The engineered switch is modular.

Quoted textsource-backed
The engineered switch is modular
Claim 5organism compatibilitysupports2020Source 1DOI

The engineered switch can be used in most organisms.

Quoted textsource-backed
can be used in most organisms