clusters of kinesin-1 motors
First-pass extracted concept
kinesin-1 motor clusters
Candidate: toolkit item1 source documents4 linked claims
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Linked Claims
A single control parameter defined by the ratio of different component concentrations dictates material-scale organization in the reported phase space.
Quoted textsource-backed
Starting from a five-dimensional organization phase space, we identify a single control parameter given by the ratio of the different component concentrations that dictates the material-scale organization.
Biochemical regulation alone is insufficient to fully explain the extensile-to-contractile transition because generic aligning interactions through depletion, cross-linking, or excluded volume can drive bundle formation despite end-accumulating motors.
Quoted textsource-backed
Finally, we show that biochemical regulation is insufficient to fully explain the transition as generic aligning interactions through depletion, cross-linking, or excluded volume interactions can drive bundle formation despite end-accumulating motors.
Microtubule-binding and unbinding kinetics of highly processive kinesin-1 motor clusters determine their ability to end-accumulate, which can drive microtubule polarity sorting and aster formation.
Quoted textsource-backed
We show that the microtubule-binding and unbinding kinetics of highly processive motor clusters set their ability to end-accumulate, which can drive polarity sorting of the microtubules and aster formation.
The microscopic time scale of motor end-accumulation sets the emergent time scale of aster formation.
Quoted textsource-backed
We further demonstrate that the microscopic time scale of end-accumulation sets the emergent time scale of aster formation.