First-pass extracted concept

nitroreductase/nitrofuran system

Candidate: toolkit item1 source documents3 linked claims
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Evidence Snippets

the nitroreductase/nitrofuran system
Evidence 1Source 1DOIPubMedprovenance

Supporting Sources

Linked Claims

Claim 1application capabilitysupports2020Source 1DOIPubMed

A light-inducible GAVPO transactivator combined with genetically encoded cell-ablation technologies enabled targeted cell ablation in zebrafish embryos with spatial and temporal control.

Quoted textsource-backed
Using this integrative approach, we have ablated cells in zebrafish embryos with both spatial and temporal control.
Claim 2comparative performancesupports2020Source 1DOIPubMed

The nitroreductase and M2 cell-ablation systems differ in ways that influence their efficacy for specific applications.

Quoted textsource-backed
Our studies also demonstrate differences between the nitroreductase and M2 systems that influence their efficacies for specific applications.
Claim 3method propertysupports2020Source 1DOIPubMed

The described ablative methods provide tissue specificity from cis-regulatory elements together with optogenetic conditionality.

Quoted textsource-backed
Our studies establish ablative methods that provide the tissue specificity afforded by cis-regulatory elements and the conditionality of optogenetics.