Herein, we report a photochromic CID system that employs the photoisomerization of a ligand so that both association and dissociation are controlled by light
First-pass extracted concept
photochromic CID system
Aliases
photochromic dimerizer
Evidence Snippets
Supporting Sources
Linked Claims
The photochromic CID system is presented as a tool to finely manipulate intracellular protein dynamics for studying diverse cellular processes.
We also demonstrated the usability of the photochromic CID system as a potential tool to finely manipulate intracellular protein dynamics to study diverse cellular processes.
The photochromic CID system is usable as a tool to finely manipulate intracellular protein dynamics for studying diverse cellular processes.
We also demonstrated the usability of the photochromic CID system as a potential tool to finely manipulate intracellular protein dynamics to study diverse cellular processes.
Using the photochromic CID system to manipulate PINK1/Parkin-mediated mitophagy, PINK1 recruitment to mitochondria promotes Parkin recruitment to proceed with mitophagy.
Utilizing this system to manipulate PINK1/Parkin-mediated mitophagy, we showed that PINK1 recruitment to the mitochondria can promote Parkin recruitment to proceed with mitophagy.
Using this system in PINK1/Parkin-mediated mitophagy, PINK1 recruitment to mitochondria promoted Parkin recruitment to proceed with mitophagy.
Utilizing this system to manipulate PINK1/Parkin-mediated mitophagy, we showed that PINK1 recruitment to the mitochondria can promote Parkin recruitment to proceed with mitophagy.
The photochromic CID system enables quick, repetitive, and quantitative regulation of target protein localization using violet and green light by controlling both association and dissociation.
Herein, we report a photochromic CID system that employs the photoisomerization of a ligand so that both association and dissociation are controlled by light, enabling quick, repetitive, and quantitative regulation of the target protein localization upon violet and green light illumination.
The reported photochromic CID system enables light-controlled association and dissociation for quick, repetitive, and quantitative regulation of target protein localization under violet and green light illumination.
Herein, we report a photochromic CID system that employs the photoisomerization of a ligand so that both association and dissociation are controlled by light, enabling quick, repetitive, and quantitative regulation of the target protein localization upon violet and green light illumination.