First-pass extracted concept

photochromic CID system

Candidate: toolkit item1 source documents6 linked claims
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Aliases

photochromic dimerizer

Evidence Snippets

Herein, we report a photochromic CID system that employs the photoisomerization of a ligand so that both association and dissociation are controlled by light
Evidence 1Source 1DOIprovenance

Supporting Sources

Linked Claims

Claim 1application scopesupports2022Source 1DOI

The photochromic CID system is presented as a tool to finely manipulate intracellular protein dynamics for studying diverse cellular processes.

Quoted textsource-backed
We also demonstrated the usability of the photochromic CID system as a potential tool to finely manipulate intracellular protein dynamics to study diverse cellular processes.
Claim 2application scopesupports2022Source 1DOI

The photochromic CID system is usable as a tool to finely manipulate intracellular protein dynamics for studying diverse cellular processes.

Quoted textsource-backed
We also demonstrated the usability of the photochromic CID system as a potential tool to finely manipulate intracellular protein dynamics to study diverse cellular processes.
Claim 3biological effectsupports2022Source 1DOI

Using the photochromic CID system to manipulate PINK1/Parkin-mediated mitophagy, PINK1 recruitment to mitochondria promotes Parkin recruitment to proceed with mitophagy.

Quoted textsource-backed
Utilizing this system to manipulate PINK1/Parkin-mediated mitophagy, we showed that PINK1 recruitment to the mitochondria can promote Parkin recruitment to proceed with mitophagy.
Claim 4biological effectsupports2022Source 1DOI

Using this system in PINK1/Parkin-mediated mitophagy, PINK1 recruitment to mitochondria promoted Parkin recruitment to proceed with mitophagy.

Quoted textsource-backed
Utilizing this system to manipulate PINK1/Parkin-mediated mitophagy, we showed that PINK1 recruitment to the mitochondria can promote Parkin recruitment to proceed with mitophagy.
Claim 5tool capabilitysupports2022Source 1DOI

The photochromic CID system enables quick, repetitive, and quantitative regulation of target protein localization using violet and green light by controlling both association and dissociation.

Quoted textsource-backed
Herein, we report a photochromic CID system that employs the photoisomerization of a ligand so that both association and dissociation are controlled by light, enabling quick, repetitive, and quantitative regulation of the target protein localization upon violet and green light illumination.
Claim 6tool capabilitysupports2022Source 1DOI

The reported photochromic CID system enables light-controlled association and dissociation for quick, repetitive, and quantitative regulation of target protein localization under violet and green light illumination.

Quoted textsource-backed
Herein, we report a photochromic CID system that employs the photoisomerization of a ligand so that both association and dissociation are controlled by light, enabling quick, repetitive, and quantitative regulation of the target protein localization upon violet and green light illumination.