First-pass extracted concept

Pseudomonas quinolone signal

Candidate: toolkit item1 source documents6 linked claims
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Aliases

2-heptyl-3-hydroxy-4-quinolone

Evidence Snippets

We report here that P. aeruginosa produces another signal molecule, 2-heptyl-3-hydroxy-4-quinolone, which has been designated as the Pseudomonas quinolone signal.
Evidence 1Source 1DOIPubMedprovenance

Supporting Sources

Linked Claims

Claim 1intercellular signaling functionsupports1999Source 1DOIPubMed

2-heptyl-3-hydroxy-4-quinolone can function as an intercellular signal in Pseudomonas aeruginosa.

Quoted textsource-backed
The demonstration that 2-heptyl-3-hydroxy-4-quinolone can function as an intercellular signal
Claim 2pathway mediationsupports1999Source 1DOIPubMed

The bioactivity of Pseudomonas quinolone signal is mediated by the rhl quorum sensing system.

Quoted textsource-backed
We also show that the synthesis and bioactivity of Pseudomonas quinolone signal were mediated by the P. aeruginosa las and rhl quorum sensing systems, respectively.
Claim 3pathway mediationsupports1999Source 1DOIPubMed

The synthesis of Pseudomonas quinolone signal is mediated by the las quorum sensing system.

Quoted textsource-backed
We also show that the synthesis and bioactivity of Pseudomonas quinolone signal were mediated by the P. aeruginosa las and rhl quorum sensing systems, respectively.
Claim 4productionsupports1999Source 1DOIPubMed

Pseudomonas aeruginosa produces the signal molecule 2-heptyl-3-hydroxy-4-quinolone, designated the Pseudomonas quinolone signal.

Quoted textsource-backed
We report here that P. aeruginosa produces another signal molecule, 2-heptyl-3-hydroxy-4-quinolone, which has been designated as the Pseudomonas quinolone signal.
Claim 5regulates gene expressionsupports1999Source 1DOIPubMed

Pseudomonas quinolone signal controls expression of lasB.

Quoted textsource-backed
It was found that this unique cell-to-cell signal controlled the expression of lasB, which encodes for the major virulence factor, LasB elastase.
Claim 6scope of signalingsupports1999Source 1DOIPubMed

Pseudomonas aeruginosa cell-to-cell signaling is not restricted to acyl-homoserine lactones.

Quoted textsource-backed
shows that P. aeruginosa cell-to-cell signaling is not restricted to acyl-homoserine lactones