First-pass extracted concept

UCNPs@TDS

Candidate: toolkit item1 source documents6 linked claims

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Aliases

near-infrared (NIR) light-activated multicomponent detection intelligent nanoprobe, UTDS

Evidence Snippets

The proposed intelligent nanoprobe is composed of a rationally designed UV light-responsive triangular DNA nano sucker (TDS) and upconversion nanoparticles (UCNPs), named UCNPs@TDS (UTDS).

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1primary paper2021Analytical ChemistryDOI PubMed

1 evidence snippet 6 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1cell entrysupports2021Source 1DOI PubMed

UCNPs@TDS can enter cells autonomously through endocytosis.

Quoted textsource-backed

which can enter cells autonomously through endocytosis

Claim 2cell line discriminationsupports2021Source 1DOI PubMed

The near-infrared light-activated UTDS can distinguish different kinds of cell lines with different miRNA expression levels.

Quoted textsource-backed

distinguishing different kinds of cell lines with different miRNA expressions levels can be also achieved through this NIR light-activated intelligent UTDS

Claim 3compositionsupports2021Source 1DOI PubMed

UCNPs@TDS is composed of a UV light-responsive triangular DNA nano sucker and upconversion nanoparticles.

Quoted textsource-backed

The proposed intelligent nanoprobe is composed of a rationally designed UV light-responsive triangular DNA nano sucker (TDS) and upconversion nanoparticles (UCNPs), named UCNPs@TDS (UTDS)

Claim 4controlled activationsupports2021Source 1DOI PubMed

UCNPs@TDS enables remote regulation of on-demand accurate imaging for multiple intracellular miRNAs using near-infrared light illumination at a chosen time and place.

Quoted textsource-backed

enable remote regulation of on-demand accurate imaging for multiple intracellular miRNAs using NIR light illumination at a chosen time and place

Claim 5developmentsupports2021Source 1DOI PubMed

The authors developed a near-infrared light-activated multicomponent detection intelligent nanoprobe for spatially and temporally controlled on-demand accurate imaging of multiple intracellular miRNAs.

Quoted textsource-backed

in this work, we developed a near-infrared (NIR) light-activated multicomponent detection intelligent nanoprobe for spatially and temporally controlled on-demand accurate imaging of multiple intracellular miRNAs

Claim 6specificity or accuracy improvementsupports2021Source 1DOI PubMed

UCNPs@TDS resists nonspecific activation, avoids false-positive signals, and improves the accuracy of imaging of multiple intracellular miRNAs.

Quoted textsource-backed

it can resist nonspecific activation as well as effectively avoid false-positive signals and improve the accuracy of imaging of multiple intracellular miRNAs