Toolkit/associating photoreceptors

associating photoreceptors

Multi-Component Switch·Research·Since 2015

Taxonomy: Mechanism Branch / Architecture. Workflows sit above the mechanism and technique branches rather than replacing them.

Summary

Associating photoreceptors are light-responsive receptors defined by changes in oligomeric state as part of light-regulated allostery. In engineered systems, they provide a multi-component switch architecture based on light-controlled association behavior.

Usefulness & Problems

Why this is useful

These receptors are useful because light-regulated association reactions are identified as powerful and versatile design principles for engineered photoreceptors. Their association-based behavior supports construction of multi-component switches controlled by light input.

Problem solved

Associating photoreceptors help solve the problem of building light-responsive systems in which multiple components are brought together or separated through illumination-dependent association. The cited evidence specifically frames this as an engineering design principle for photoreceptor-based control.

Problem links

Need precise spatiotemporal control with light input

Derived

Associating photoreceptors are a class of light-responsive receptors that change oligomeric state as part of light-regulated allostery. In engineered systems, they provide a multi-component switch architecture based on light-controlled association behavior.

Taxonomy & Function

Primary hierarchy

Mechanism Branch

Architecture: A composed arrangement of multiple parts that instantiates one or more mechanisms.

Techniques

No technique tags yet.

Target processes

No target processes tagged yet.

Input: Light

Implementation Constraints

cofactor dependency: cofactor requirement unknownencoding mode: genetically encodedimplementation constraint: context specific validationimplementation constraint: multi component delivery burdenimplementation constraint: spectral hardware requirementoperating role: actuatorswitch architecture: multi component

The evidence supports use of associating photoreceptors in engineered constructs through domain fusion. However, no specific photoreceptor family, chromophore requirement, construct topology, or expression context is described in the supplied material.

The supplied evidence is conceptual and classification-level rather than tool-specific performance data. No quantitative kinetics, dynamic range, wavelength specificity, host-system validation, or independent benchmarking are provided here.

Validation

Cell-freeBacteriaMammalianMouseHumanTherapeuticIndep. Replication

Supporting Sources

Ranked Claims

Claim 1classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 2classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 3classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 4classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 5classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 6classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 7classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 8classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 9classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 10classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 11classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 12classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 13classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 14classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 15classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 16classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 17classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 18classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 19classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 20classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 21classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 22classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 23classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 24classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 25classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 26classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 27classificationsupports2015Source 1needs review

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.
Claim 28design principlesupports2015Source 1needs review

Light-regulated association reactions and order-disorder transitions are highlighted as particularly powerful and versatile design principles in engineered photoreceptors.

A survey of engineered photoreceptors pinpoints light-regulated association reactions and order-disorder transitions as particularly powerful and versatile design principles.
Claim 29design principlesupports2015Source 1needs review

Light-regulated association reactions and order-disorder transitions are highlighted as particularly powerful and versatile design principles in engineered photoreceptors.

A survey of engineered photoreceptors pinpoints light-regulated association reactions and order-disorder transitions as particularly powerful and versatile design principles.
Claim 30design principlesupports2015Source 1needs review

Light-regulated association reactions and order-disorder transitions are highlighted as particularly powerful and versatile design principles in engineered photoreceptors.

A survey of engineered photoreceptors pinpoints light-regulated association reactions and order-disorder transitions as particularly powerful and versatile design principles.
Claim 31design principlesupports2015Source 1needs review

Light-regulated association reactions and order-disorder transitions are highlighted as particularly powerful and versatile design principles in engineered photoreceptors.

A survey of engineered photoreceptors pinpoints light-regulated association reactions and order-disorder transitions as particularly powerful and versatile design principles.
Claim 32design principlesupports2015Source 1needs review

Light-regulated association reactions and order-disorder transitions are highlighted as particularly powerful and versatile design principles in engineered photoreceptors.

A survey of engineered photoreceptors pinpoints light-regulated association reactions and order-disorder transitions as particularly powerful and versatile design principles.
Claim 33design principlesupports2015Source 1needs review

Light-regulated association reactions and order-disorder transitions are highlighted as particularly powerful and versatile design principles in engineered photoreceptors.

A survey of engineered photoreceptors pinpoints light-regulated association reactions and order-disorder transitions as particularly powerful and versatile design principles.
Claim 34design principlesupports2015Source 1needs review

Light-regulated association reactions and order-disorder transitions are highlighted as particularly powerful and versatile design principles in engineered photoreceptors.

A survey of engineered photoreceptors pinpoints light-regulated association reactions and order-disorder transitions as particularly powerful and versatile design principles.
Claim 35design principlesupports2015Source 1needs review

Light-regulated association reactions and order-disorder transitions are highlighted as particularly powerful and versatile design principles in engineered photoreceptors.

A survey of engineered photoreceptors pinpoints light-regulated association reactions and order-disorder transitions as particularly powerful and versatile design principles.
Claim 36design principlesupports2015Source 1needs review

Light-regulated association reactions and order-disorder transitions are highlighted as particularly powerful and versatile design principles in engineered photoreceptors.

A survey of engineered photoreceptors pinpoints light-regulated association reactions and order-disorder transitions as particularly powerful and versatile design principles.
Claim 37design principlesupports2015Source 1needs review

Light-regulated association reactions and order-disorder transitions are highlighted as particularly powerful and versatile design principles in engineered photoreceptors.

A survey of engineered photoreceptors pinpoints light-regulated association reactions and order-disorder transitions as particularly powerful and versatile design principles.
Claim 38design principlesupports2015Source 1needs review

Light-regulated association reactions and order-disorder transitions are highlighted as particularly powerful and versatile design principles in engineered photoreceptors.

A survey of engineered photoreceptors pinpoints light-regulated association reactions and order-disorder transitions as particularly powerful and versatile design principles.
Claim 39design principlesupports2015Source 1needs review

Light-regulated association reactions and order-disorder transitions are highlighted as particularly powerful and versatile design principles in engineered photoreceptors.

A survey of engineered photoreceptors pinpoints light-regulated association reactions and order-disorder transitions as particularly powerful and versatile design principles.
Claim 40design principlesupports2015Source 1needs review

Light-regulated association reactions and order-disorder transitions are highlighted as particularly powerful and versatile design principles in engineered photoreceptors.

A survey of engineered photoreceptors pinpoints light-regulated association reactions and order-disorder transitions as particularly powerful and versatile design principles.
Claim 41design principlesupports2015Source 1needs review

Light-regulated association reactions and order-disorder transitions are highlighted as particularly powerful and versatile design principles in engineered photoreceptors.

A survey of engineered photoreceptors pinpoints light-regulated association reactions and order-disorder transitions as particularly powerful and versatile design principles.
Claim 42design principlesupports2015Source 1needs review

Light-regulated association reactions and order-disorder transitions are highlighted as particularly powerful and versatile design principles in engineered photoreceptors.

A survey of engineered photoreceptors pinpoints light-regulated association reactions and order-disorder transitions as particularly powerful and versatile design principles.
Claim 43design principlesupports2015Source 1needs review

Light-regulated association reactions and order-disorder transitions are highlighted as particularly powerful and versatile design principles in engineered photoreceptors.

A survey of engineered photoreceptors pinpoints light-regulated association reactions and order-disorder transitions as particularly powerful and versatile design principles.
Claim 44design principlesupports2015Source 1needs review

Light-regulated association reactions and order-disorder transitions are highlighted as particularly powerful and versatile design principles in engineered photoreceptors.

A survey of engineered photoreceptors pinpoints light-regulated association reactions and order-disorder transitions as particularly powerful and versatile design principles.
Claim 45design principlesupports2015Source 1needs review

Light-regulated association reactions and order-disorder transitions are highlighted as particularly powerful and versatile design principles in engineered photoreceptors.

A survey of engineered photoreceptors pinpoints light-regulated association reactions and order-disorder transitions as particularly powerful and versatile design principles.
Claim 46design principlesupports2015Source 1needs review

Light-regulated association reactions and order-disorder transitions are highlighted as particularly powerful and versatile design principles in engineered photoreceptors.

A survey of engineered photoreceptors pinpoints light-regulated association reactions and order-disorder transitions as particularly powerful and versatile design principles.
Claim 47design principlesupports2015Source 1needs review

Light-regulated association reactions and order-disorder transitions are highlighted as particularly powerful and versatile design principles in engineered photoreceptors.

A survey of engineered photoreceptors pinpoints light-regulated association reactions and order-disorder transitions as particularly powerful and versatile design principles.

Approval Evidence

1 source1 linked approval claimfirst-pass slug associating-photoreceptors
Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery.

Source:

classificationsupports

Photoreceptors can be divided into associating receptors that alter oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Photoreceptors dichotomize into associating receptors that alter their oligomeric state as part of light-regulated allostery and non-associating receptors that do not.

Source:

Comparisons

Source-backed strengths

The available evidence highlights light-regulated association as a particularly powerful and versatile design principle. Associating photoreceptors are also mechanistically distinct in that they alter oligomeric state as part of light-regulated allostery, which directly supports switch-like multi-component control.

Compared with AQTrip EL222 variant

associating photoreceptors and AQTrip EL222 variant address a similar problem space.

Shared frame: same top-level item type; shared mechanisms: oligomerization; same primary input modality: light

Compared with OptoLoop

associating photoreceptors and OptoLoop address a similar problem space.

Shared frame: same top-level item type; shared mechanisms: oligomerization; same primary input modality: light

Compared with optoRET

associating photoreceptors and optoRET address a similar problem space.

Shared frame: same top-level item type; shared mechanisms: oligomerization; same primary input modality: light

Ranked Citations

  1. 1.
    StructuralSource 1Frontiers in Molecular Biosciences2015Claim 26Claim 27Claim 26

    Seeded from load plan for claim cl2. Extracted from this source document.