Source 1review2018Organic & Biomolecular Chemistry
Toolkit/azobenzene-based molecular photoswitches
azobenzene-based molecular photoswitches
Also known as: azobenzene-based small molecular photoswitches, molecular photoswitches
Taxonomy: Mechanism Branch / Component. Workflows sit above the mechanism and technique branches rather than replacing them.
Summary
Molecular photoswitches are a class of chemical structures that can readily isomerize between distinct geometries upon irradiation with light. Molecular photoswitches are utilized to control protein structure and function with temporal and spatial precision. In this review, we summarize the recent progress in the development of azobenzene-based molecular photoswitches and their applications in the photocontrol of protein structure and function.
Usefulness & Problems
No literature-backed usefulness or problem-fit explainer has been materialized for this record yet.
Published Workflows
Objective: Design azobenzene-based photoswitchable ligands that enable optical control of protein structure and function.
Why it works: The review links light-driven geometric isomerization of azobenzene-based photoswitches to the ability to modulate protein structure and function with temporal and spatial precision.
light-induced isomerization between distinct geometriesphotocontrol of protein structure and functionstructure-guided ligand design
Taxonomy & Function
Primary hierarchy
Mechanism Branch
Component: A low-level protein part used inside a larger architecture that realizes a mechanism.
Techniques
No technique tags yet.
Target processes
No target processes tagged yet.
Input: Light
Validation
Cell-freeBacteriaMammalianMouseHumanTherapeuticIndep. Replication
Supporting Sources
Ranked Claims
Azobenzene-based molecular photoswitches are used to control protein structure and function with temporal and spatial precision.
Molecular photoswitches are utilized to control protein structure and function with temporal and spatial precision.
Structure-guided design is a basic approach discussed for creating photoswitchable ligands.
Basic approaches and considerations for the structure-guided design of photoswitchable ligands are discussed.
Molecular photoswitches can isomerize between distinct geometries upon light irradiation.
Molecular photoswitches are a class of chemical structures that can readily isomerize between distinct geometries upon irradiation with light.
Current azobenzene-based photoswitches have limitations that are discussed in the review.
The applications and limitations of current photoswitches are also discussed.
Approval Evidence
1 source3 linked approval claimsfirst-pass slug azobenzene-based-molecular-photoswitches
Molecular photoswitches are a class of chemical structures that can readily isomerize between distinct geometries upon irradiation with light. Molecular photoswitches are utilized to control protein structure and function with temporal and spatial precision. In this review, we summarize the recent progress in the development of azobenzene-based molecular photoswitches and their applications in the photocontrol of protein structure and function.
Source:
application scopesupports
Azobenzene-based molecular photoswitches are used to control protein structure and function with temporal and spatial precision.
Molecular photoswitches are utilized to control protein structure and function with temporal and spatial precision.
Source:
functional capabilitysupports
Molecular photoswitches can isomerize between distinct geometries upon light irradiation.
Molecular photoswitches are a class of chemical structures that can readily isomerize between distinct geometries upon irradiation with light.
Source:
limitation statementsupports
Current azobenzene-based photoswitches have limitations that are discussed in the review.
The applications and limitations of current photoswitches are also discussed.
Source:
Comparisons
No literature-backed comparison notes have been materialized for this record yet.
Ranked Citations
- 1.