Source 1primary paper2023International Journal of Molecular Sciences
Toolkit/basic helix-loop-helix transcription factor family in Chimonanthus praecox
basic helix-loop-helix transcription factor family in Chimonanthus praecox
Also known as: bHLH transcription factor family in Wintersweet, CpbHLH gene family
Taxonomy: Mechanism Branch / Component. Workflows sit above the mechanism and technique branches rather than replacing them.
Summary
The CpbHLH gene family is the set of basic helix-loop-helix transcription factor genes identified in Chimonanthus praecox. A genome-wide study reported 131 CpbHLH genes distributed across 11 chromosomes and characterized their expression across tissues and flower developmental stages.
Usefulness & Problems
Why this is useful
This gene family resource is useful for studying transcriptional regulation in Wintersweet and for prioritizing candidate regulators associated with tissue-specific and flower stage-specific biology. The reported expression diversity and evolutionary analysis provide a framework for comparative and functional studies within this ornamental species.
Problem solved
It addresses the lack of a genome-wide catalog and initial characterization of bHLH transcription factors in Chimonanthus praecox. The study also provides an initial view of how this family expanded, indicating segmental duplication and purifying selection among duplicated pairs.
Taxonomy & Function
Primary hierarchy
Mechanism Branch
Component: A low-level protein part used inside a larger architecture that realizes a mechanism.
Mechanisms
transcriptional regulationTarget processes
selectiontranscriptionImplementation Constraints
Implementation is as a genomic and transcriptomic candidate set in Chimonanthus praecox rather than as a single engineered reagent. Practical use therefore depends on access to the Wintersweet genome context and follow-up expression or functional assays for individual CpbHLH genes.
The available evidence describes identification, chromosomal distribution, expression patterns, and evolutionary inference, but does not provide direct functional validation for specific CpbHLH proteins. Independent replication and mechanistic dissection beyond general transcriptional regulation are not documented in the supplied evidence.
Validation
Cell-freeBacteriaMammalianMouseHumanTherapeuticIndep. Replication
Supporting Sources
Ranked Claims
CpbHLH genes show diverse expression patterns across tissues and flower developmental stages in Wintersweet, suggesting involvement in diverse physiological processes.
Transcriptomic analysis revealed diverse expression patterns of CpbHLH genes in various tissues and distinct stages of Wintersweet flower development, thereby suggesting their involvement in a diverse array of physiological processes
CpbHLH genes show diverse expression patterns across tissues and flower developmental stages in Wintersweet, suggesting involvement in diverse physiological processes.
Transcriptomic analysis revealed diverse expression patterns of CpbHLH genes in various tissues and distinct stages of Wintersweet flower development, thereby suggesting their involvement in a diverse array of physiological processes
CpbHLH genes show diverse expression patterns across tissues and flower developmental stages in Wintersweet, suggesting involvement in diverse physiological processes.
Transcriptomic analysis revealed diverse expression patterns of CpbHLH genes in various tissues and distinct stages of Wintersweet flower development, thereby suggesting their involvement in a diverse array of physiological processes
CpbHLH genes show diverse expression patterns across tissues and flower developmental stages in Wintersweet, suggesting involvement in diverse physiological processes.
Transcriptomic analysis revealed diverse expression patterns of CpbHLH genes in various tissues and distinct stages of Wintersweet flower development, thereby suggesting their involvement in a diverse array of physiological processes
CpbHLH genes show diverse expression patterns across tissues and flower developmental stages in Wintersweet, suggesting involvement in diverse physiological processes.
Transcriptomic analysis revealed diverse expression patterns of CpbHLH genes in various tissues and distinct stages of Wintersweet flower development, thereby suggesting their involvement in a diverse array of physiological processes
CpbHLH genes show diverse expression patterns across tissues and flower developmental stages in Wintersweet, suggesting involvement in diverse physiological processes.
Transcriptomic analysis revealed diverse expression patterns of CpbHLH genes in various tissues and distinct stages of Wintersweet flower development, thereby suggesting their involvement in a diverse array of physiological processes
CpbHLH genes show diverse expression patterns across tissues and flower developmental stages in Wintersweet, suggesting involvement in diverse physiological processes.
Transcriptomic analysis revealed diverse expression patterns of CpbHLH genes in various tissues and distinct stages of Wintersweet flower development, thereby suggesting their involvement in a diverse array of physiological processes
Expansion of the CpbHLH gene family was primarily driven by segmental duplication, and duplicated gene pairs experienced purifying selection during evolution.
the expansion of the CpbHLH gene family was primarily driven by segmental duplication, with duplicated gene pairs experiencing purifying selection during evolution
Expansion of the CpbHLH gene family was primarily driven by segmental duplication, and duplicated gene pairs experienced purifying selection during evolution.
the expansion of the CpbHLH gene family was primarily driven by segmental duplication, with duplicated gene pairs experiencing purifying selection during evolution
Expansion of the CpbHLH gene family was primarily driven by segmental duplication, and duplicated gene pairs experienced purifying selection during evolution.
the expansion of the CpbHLH gene family was primarily driven by segmental duplication, with duplicated gene pairs experiencing purifying selection during evolution
Expansion of the CpbHLH gene family was primarily driven by segmental duplication, and duplicated gene pairs experienced purifying selection during evolution.
the expansion of the CpbHLH gene family was primarily driven by segmental duplication, with duplicated gene pairs experiencing purifying selection during evolution
Expansion of the CpbHLH gene family was primarily driven by segmental duplication, and duplicated gene pairs experienced purifying selection during evolution.
the expansion of the CpbHLH gene family was primarily driven by segmental duplication, with duplicated gene pairs experiencing purifying selection during evolution
Expansion of the CpbHLH gene family was primarily driven by segmental duplication, and duplicated gene pairs experienced purifying selection during evolution.
the expansion of the CpbHLH gene family was primarily driven by segmental duplication, with duplicated gene pairs experiencing purifying selection during evolution
Expansion of the CpbHLH gene family was primarily driven by segmental duplication, and duplicated gene pairs experienced purifying selection during evolution.
the expansion of the CpbHLH gene family was primarily driven by segmental duplication, with duplicated gene pairs experiencing purifying selection during evolution
The Chimonanthus praecox bHLH gene family comprises 131 identified genes across 11 chromosomes.
identifying a total of 131 CpbHLH genes across 11 chromosomes
chromosome count 11identified genes 131
The Chimonanthus praecox bHLH gene family comprises 131 identified genes across 11 chromosomes.
identifying a total of 131 CpbHLH genes across 11 chromosomes
chromosome count 11identified genes 131
The Chimonanthus praecox bHLH gene family comprises 131 identified genes across 11 chromosomes.
identifying a total of 131 CpbHLH genes across 11 chromosomes
chromosome count 11identified genes 131
The Chimonanthus praecox bHLH gene family comprises 131 identified genes across 11 chromosomes.
identifying a total of 131 CpbHLH genes across 11 chromosomes
chromosome count 11identified genes 131
The Chimonanthus praecox bHLH gene family comprises 131 identified genes across 11 chromosomes.
identifying a total of 131 CpbHLH genes across 11 chromosomes
chromosome count 11identified genes 131
The Chimonanthus praecox bHLH gene family comprises 131 identified genes across 11 chromosomes.
identifying a total of 131 CpbHLH genes across 11 chromosomes
chromosome count 11identified genes 131
The Chimonanthus praecox bHLH gene family comprises 131 identified genes across 11 chromosomes.
identifying a total of 131 CpbHLH genes across 11 chromosomes
chromosome count 11identified genes 131
Phylogenetic analysis classified the CpbHLH genes into 23 subfamilies.
Phylogenetic analysis classified these CpbHLH genes into 23 subfamilies
subfamily count 23
Phylogenetic analysis classified the CpbHLH genes into 23 subfamilies.
Phylogenetic analysis classified these CpbHLH genes into 23 subfamilies
subfamily count 23
Phylogenetic analysis classified the CpbHLH genes into 23 subfamilies.
Phylogenetic analysis classified these CpbHLH genes into 23 subfamilies
subfamily count 23
Phylogenetic analysis classified the CpbHLH genes into 23 subfamilies.
Phylogenetic analysis classified these CpbHLH genes into 23 subfamilies
subfamily count 23
Phylogenetic analysis classified the CpbHLH genes into 23 subfamilies.
Phylogenetic analysis classified these CpbHLH genes into 23 subfamilies
subfamily count 23
Phylogenetic analysis classified the CpbHLH genes into 23 subfamilies.
Phylogenetic analysis classified these CpbHLH genes into 23 subfamilies
subfamily count 23
Phylogenetic analysis classified the CpbHLH genes into 23 subfamilies.
Phylogenetic analysis classified these CpbHLH genes into 23 subfamilies
subfamily count 23
Most CpbHLH members within the same subfamily showed similar intron/exon patterns and motif composition.
most members within the same subfamily exhibited analogous intron/exon patterns and motif composition
Most CpbHLH members within the same subfamily showed similar intron/exon patterns and motif composition.
most members within the same subfamily exhibited analogous intron/exon patterns and motif composition
Most CpbHLH members within the same subfamily showed similar intron/exon patterns and motif composition.
most members within the same subfamily exhibited analogous intron/exon patterns and motif composition
Most CpbHLH members within the same subfamily showed similar intron/exon patterns and motif composition.
most members within the same subfamily exhibited analogous intron/exon patterns and motif composition
Most CpbHLH members within the same subfamily showed similar intron/exon patterns and motif composition.
most members within the same subfamily exhibited analogous intron/exon patterns and motif composition
Most CpbHLH members within the same subfamily showed similar intron/exon patterns and motif composition.
most members within the same subfamily exhibited analogous intron/exon patterns and motif composition
Most CpbHLH members within the same subfamily showed similar intron/exon patterns and motif composition.
most members within the same subfamily exhibited analogous intron/exon patterns and motif composition
Approval Evidence
1 source5 linked approval claimsfirst-pass slug basic-helix-loop-helix-transcription-factor-family-in-chimonanthus-praecox
we conducted a comprehensive genome-wide analysis of the C. praecox bHLH (CpbHLH) gene family
Source:
expression patternsupports
CpbHLH genes show diverse expression patterns across tissues and flower developmental stages in Wintersweet, suggesting involvement in diverse physiological processes.
Transcriptomic analysis revealed diverse expression patterns of CpbHLH genes in various tissues and distinct stages of Wintersweet flower development, thereby suggesting their involvement in a diverse array of physiological processes
Source:
gene family expansion mechanismsupports
Expansion of the CpbHLH gene family was primarily driven by segmental duplication, and duplicated gene pairs experienced purifying selection during evolution.
the expansion of the CpbHLH gene family was primarily driven by segmental duplication, with duplicated gene pairs experiencing purifying selection during evolution
Source:
genome wide identificationsupports
The Chimonanthus praecox bHLH gene family comprises 131 identified genes across 11 chromosomes.
identifying a total of 131 CpbHLH genes across 11 chromosomes
Source:
phylogenetic classificationsupports
Phylogenetic analysis classified the CpbHLH genes into 23 subfamilies.
Phylogenetic analysis classified these CpbHLH genes into 23 subfamilies
Source:
structural similarity within subfamiliessupports
Most CpbHLH members within the same subfamily showed similar intron/exon patterns and motif composition.
most members within the same subfamily exhibited analogous intron/exon patterns and motif composition
Source:
Comparisons
Source-backed strengths
The family was analyzed at genome scale, with 131 genes identified across 11 chromosomes. Expression profiling across tissues and flower developmental stages showed diverse patterns, supporting potential roles in multiple physiological processes. Evolutionary analysis further linked family expansion primarily to segmental duplication.
Ranked Citations
- 1.