Source 1review2017Annual Review of Biochemistry
Toolkit/cation channelrhodopsins
cation channelrhodopsins
Also known as: CCRs, cryptophyte cation channelrhodopsins
Taxonomy: Mechanism Branch / Component. Workflows sit above the mechanism and technique branches rather than replacing them.
Summary
(b) cryptophyte cation channelrhodopsins (CCRs), structurally distinct from the green algae CCRs used extensively for neural activation and from cryptophyte ACRs
Usefulness & Problems
No literature-backed usefulness or problem-fit explainer has been materialized for this record yet.
Taxonomy & Function
Primary hierarchy
Mechanism Branch
Component: A low-level protein part used inside a larger architecture that realizes a mechanism.
Mechanisms
light-gated ion channel activityTechniques
Structural CharacterizationTarget processes
No target processes tagged yet.
Validation
Cell-freeBacteriaMammalianMouseHumanTherapeuticIndep. Replication
Supporting Sources
Ranked Claims
Cryptophyte cation channelrhodopsins are structurally distinct from green algae cation channelrhodopsins and from cryptophyte anion channelrhodopsins.
Cryptophyte anion channelrhodopsins enable efficient optogenetic neural suppression.
Green algae cation channelrhodopsins have been used extensively for neural activation.
Approval Evidence
1 source2 linked approval claimsfirst-pass slug cation-channelrhodopsins
(b) cryptophyte cation channelrhodopsins (CCRs), structurally distinct from the green algae CCRs used extensively for neural activation and from cryptophyte ACRs
Source:
structural distinctnesssupports
Cryptophyte cation channelrhodopsins are structurally distinct from green algae cation channelrhodopsins and from cryptophyte anion channelrhodopsins.
Source:
tool functionsupports
Green algae cation channelrhodopsins have been used extensively for neural activation.
Source:
Comparisons
No literature-backed comparison notes have been materialized for this record yet.
Ranked Citations
- 1.