Source 1primary paper2017
Toolkit/feed-forward and feedback control technique
feed-forward and feedback control technique
Taxonomy: Technique Branch / Method. Workflows sit above the mechanism and technique branches rather than replacing them.
Summary
The feed-forward and feedback control technique is an engineering method proposed for astrocytes that manipulates intracellular IP3 to stabilize Ca2+ concentration. It is described in the context of Ca2+-based molecular communications nanonetworks, where controlled Ca2+ dynamics are intended to support more reliable signaling behavior.
Usefulness & Problems
Why this is useful
This method is useful because it aims to maintain astrocytic Ca2+ around a desired level and thereby prevent abnormal gliotransmitter concentration. In the cited molecular communication framework, maintaining Ca2+ refractory periods is also associated with lower noise propagation, smaller time-slots for bit transmission, and improved delay and gain performance.
Problem solved
The specific problem addressed is instability in intracellular Ca2+ dynamics in astrocytes, which can lead to abnormal gliotransmitter concentration. The method also targets communication-level impairments in Ca2+-based nanonetworks, including noise propagation and inefficient transmission timing.
Taxonomy & Function
Primary hierarchy
Technique Branch
Method: A concrete method used to build, optimize, or evolve an engineered system.
Techniques
No technique tags yet.
Target processes
No target processes tagged yet.
Implementation Constraints
Implementation is described at the level of control design that manipulates IP3 values to regulate intracellular Ca2+ in astrocytes. The supplied evidence does not specify construct design, delivery modality, molecular actuators, or experimental expression system details.
The available evidence is limited to a single 2017 source and describes the technique as a proposed control strategy in a modeling context. The supplied evidence does not report independent replication, experimental implementation in living astrocytes, or quantitative performance benchmarks.
Validation
Cell-freeBacteriaMammalianMouseHumanTherapeuticIndep. Replication
Supporting Sources
Ranked Claims
The model aims to stabilize Ca2+ concentration around a desired level to prevent abnormal gliotransmitter concentration.
The theoretical analysis of the given model aims i) to stabilize the Ca 2+ concentration around a particular desired level in order to prevent abnormal gliotransmitters’ concentration
The model aims to stabilize Ca2+ concentration around a desired level to prevent abnormal gliotransmitter concentration.
The theoretical analysis of the given model aims i) to stabilize the Ca 2+ concentration around a particular desired level in order to prevent abnormal gliotransmitters’ concentration
The model aims to stabilize Ca2+ concentration around a desired level to prevent abnormal gliotransmitter concentration.
The theoretical analysis of the given model aims i) to stabilize the Ca 2+ concentration around a particular desired level in order to prevent abnormal gliotransmitters’ concentration
The model aims to stabilize Ca2+ concentration around a desired level to prevent abnormal gliotransmitter concentration.
The theoretical analysis of the given model aims i) to stabilize the Ca 2+ concentration around a particular desired level in order to prevent abnormal gliotransmitters’ concentration
The model aims to stabilize Ca2+ concentration around a desired level to prevent abnormal gliotransmitter concentration.
The theoretical analysis of the given model aims i) to stabilize the Ca 2+ concentration around a particular desired level in order to prevent abnormal gliotransmitters’ concentration
The model aims to stabilize Ca2+ concentration around a desired level to prevent abnormal gliotransmitter concentration.
The theoretical analysis of the given model aims i) to stabilize the Ca 2+ concentration around a particular desired level in order to prevent abnormal gliotransmitters’ concentration
The model aims to stabilize Ca2+ concentration around a desired level to prevent abnormal gliotransmitter concentration.
The theoretical analysis of the given model aims i) to stabilize the Ca 2+ concentration around a particular desired level in order to prevent abnormal gliotransmitters’ concentration
A feed-forward and feedback control technique is used to manipulate IP3 values to stabilize Ca2+ concentration inside astrocytes.
A feed-forward and feedback control technique is used to manipulate IP 3 values to stabilise the concentration of Ca 2+ inside the astrocytes.
A feed-forward and feedback control technique is used to manipulate IP3 values to stabilize Ca2+ concentration inside astrocytes.
A feed-forward and feedback control technique is used to manipulate IP 3 values to stabilise the concentration of Ca 2+ inside the astrocytes.
A feed-forward and feedback control technique is used to manipulate IP3 values to stabilize Ca2+ concentration inside astrocytes.
A feed-forward and feedback control technique is used to manipulate IP 3 values to stabilise the concentration of Ca 2+ inside the astrocytes.
A feed-forward and feedback control technique is used to manipulate IP3 values to stabilize Ca2+ concentration inside astrocytes.
A feed-forward and feedback control technique is used to manipulate IP 3 values to stabilise the concentration of Ca 2+ inside the astrocytes.
A feed-forward and feedback control technique is used to manipulate IP3 values to stabilize Ca2+ concentration inside astrocytes.
A feed-forward and feedback control technique is used to manipulate IP 3 values to stabilise the concentration of Ca 2+ inside the astrocytes.
A feed-forward and feedback control technique is used to manipulate IP3 values to stabilize Ca2+ concentration inside astrocytes.
A feed-forward and feedback control technique is used to manipulate IP 3 values to stabilise the concentration of Ca 2+ inside the astrocytes.
A feed-forward and feedback control technique is used to manipulate IP3 values to stabilize Ca2+ concentration inside astrocytes.
A feed-forward and feedback control technique is used to manipulate IP 3 values to stabilise the concentration of Ca 2+ inside the astrocytes.
Maintaining Ca2+ refractory periods lowers noise propagation, enables smaller time-slots for bit transmission, and can improve delay and gain performances.
It shows that the refractory periods from Ca 2+ can be maintained to lower the noise propagation resulting in smaller time-slots for bit transmission, which can also improve the delay and gain performances.
Maintaining Ca2+ refractory periods lowers noise propagation, enables smaller time-slots for bit transmission, and can improve delay and gain performances.
It shows that the refractory periods from Ca 2+ can be maintained to lower the noise propagation resulting in smaller time-slots for bit transmission, which can also improve the delay and gain performances.
Maintaining Ca2+ refractory periods lowers noise propagation, enables smaller time-slots for bit transmission, and can improve delay and gain performances.
It shows that the refractory periods from Ca 2+ can be maintained to lower the noise propagation resulting in smaller time-slots for bit transmission, which can also improve the delay and gain performances.
Maintaining Ca2+ refractory periods lowers noise propagation, enables smaller time-slots for bit transmission, and can improve delay and gain performances.
It shows that the refractory periods from Ca 2+ can be maintained to lower the noise propagation resulting in smaller time-slots for bit transmission, which can also improve the delay and gain performances.
Maintaining Ca2+ refractory periods lowers noise propagation, enables smaller time-slots for bit transmission, and can improve delay and gain performances.
It shows that the refractory periods from Ca 2+ can be maintained to lower the noise propagation resulting in smaller time-slots for bit transmission, which can also improve the delay and gain performances.
Maintaining Ca2+ refractory periods lowers noise propagation, enables smaller time-slots for bit transmission, and can improve delay and gain performances.
It shows that the refractory periods from Ca 2+ can be maintained to lower the noise propagation resulting in smaller time-slots for bit transmission, which can also improve the delay and gain performances.
Maintaining Ca2+ refractory periods lowers noise propagation, enables smaller time-slots for bit transmission, and can improve delay and gain performances.
It shows that the refractory periods from Ca 2+ can be maintained to lower the noise propagation resulting in smaller time-slots for bit transmission, which can also improve the delay and gain performances.
Approval Evidence
1 source3 linked approval claimsfirst-pass slug feed-forward-and-feedback-control-technique
A feed-forward and feedback control technique is used to manipulate IP 3 values to stabilise the concentration of Ca 2+ inside the astrocytes.
Source:
intended benefitsupports
The model aims to stabilize Ca2+ concentration around a desired level to prevent abnormal gliotransmitter concentration.
The theoretical analysis of the given model aims i) to stabilize the Ca 2+ concentration around a particular desired level in order to prevent abnormal gliotransmitters’ concentration
Source:
method functionsupports
A feed-forward and feedback control technique is used to manipulate IP3 values to stabilize Ca2+ concentration inside astrocytes.
A feed-forward and feedback control technique is used to manipulate IP 3 values to stabilise the concentration of Ca 2+ inside the astrocytes.
Source:
performance effectsupports
Maintaining Ca2+ refractory periods lowers noise propagation, enables smaller time-slots for bit transmission, and can improve delay and gain performances.
It shows that the refractory periods from Ca 2+ can be maintained to lower the noise propagation resulting in smaller time-slots for bit transmission, which can also improve the delay and gain performances.
Source:
Comparisons
Source-backed strengths
The reported strength of the approach is that it directly regulates IP3, a control point used to stabilize intracellular Ca2+ in astrocytes. The source further claims system-level benefits in Ca2+-based molecular communications, including reduced noise propagation and improved delay and gain characteristics.
Source:
It shows that the refractory periods from Ca 2+ can be maintained to lower the noise propagation resulting in smaller time-slots for bit transmission, which can also improve the delay and gain performances.
Ranked Citations
- 1.