Source 1primary paper2008PLANT PHYSIOLOGY
Toolkit/H3K27me3
H3K27me3
Taxonomy: Mechanism Branch / Component. Workflows sit above the mechanism and technique branches rather than replacing them.
Summary
H3K27me3 is a histone H3 lysine 27 trimethylation mark examined in Arabidopsis as one of four chromatin modifications associated with light-regulated transcription. In the cited study, changes in H3K27me3 were analyzed in relation to changing light conditions and gene expression.
Usefulness & Problems
Why this is useful
H3K27me3 is useful as an epigenetic readout for studying how changing light environments are linked to transcriptional regulation in plants. The cited evidence supports its use in correlating chromatin state with light-responsive gene expression and photoreceptor-dependent signaling.
Source:
our data suggest that light-regulated changes in histone modifications might be an intricate part of light-controlled gene transcription
Problem solved
This mark helps address the problem of how light signals are connected to chromatin-level regulation of transcription in Arabidopsis. Specifically, the study uses H3K27me3 to examine whether histone modification changes form part of light-controlled gene regulation.
Taxonomy & Function
Primary hierarchy
Mechanism Branch
Component: A low-level protein part used inside a larger architecture that realizes a mechanism.
Mechanisms
cooperative association between histone modification state and transcriptioncooperative regulation between histone modification state and transcriptionlight-regulated chromatin modificationphotoreceptor-mediated regulation of histone modificationTechniques
No technique tags yet.
Target processes
transcriptionInput: Light
Implementation Constraints
The available evidence supports use in Arabidopsis under changing light conditions with parallel measurement of transcription and histone modification state. No construct architecture, delivery method, exogenous cofactor requirement, or protein-domain engineering details are provided in the supplied material.
The supplied evidence describes H3K27me3 primarily as an observed endogenous histone mark rather than an engineered biological tool. No evidence is provided here for causal manipulation, construct design, quantitative performance, or validation beyond the cited Arabidopsis light-response context.
Validation
Cell-freeBacteriaMammalianMouseHumanTherapeuticIndep. Replication
Supporting Sources
Ranked Claims
Light-regulated changes in histone modifications may be an intricate part of light-controlled gene transcription.
our data suggest that light-regulated changes in histone modifications might be an intricate part of light-controlled gene transcription
Light-regulated changes in histone modifications may be an intricate part of light-controlled gene transcription.
our data suggest that light-regulated changes in histone modifications might be an intricate part of light-controlled gene transcription
Light-regulated changes in histone modifications may be an intricate part of light-controlled gene transcription.
our data suggest that light-regulated changes in histone modifications might be an intricate part of light-controlled gene transcription
Light-regulated changes in histone modifications may be an intricate part of light-controlled gene transcription.
our data suggest that light-regulated changes in histone modifications might be an intricate part of light-controlled gene transcription
Light-regulated changes in histone modifications may be an intricate part of light-controlled gene transcription.
our data suggest that light-regulated changes in histone modifications might be an intricate part of light-controlled gene transcription
Light-regulated changes in histone modifications may be an intricate part of light-controlled gene transcription.
our data suggest that light-regulated changes in histone modifications might be an intricate part of light-controlled gene transcription
Light-regulated changes in histone modifications may be an intricate part of light-controlled gene transcription.
our data suggest that light-regulated changes in histone modifications might be an intricate part of light-controlled gene transcription
Distinct photoreceptor systems mediate the effects of different light qualities on histone modifications.
Distinct photoreceptor systems are responsible for mediating the effects of different light qualities on histone modifications.
Distinct photoreceptor systems mediate the effects of different light qualities on histone modifications.
Distinct photoreceptor systems are responsible for mediating the effects of different light qualities on histone modifications.
Distinct photoreceptor systems mediate the effects of different light qualities on histone modifications.
Distinct photoreceptor systems are responsible for mediating the effects of different light qualities on histone modifications.
Distinct photoreceptor systems mediate the effects of different light qualities on histone modifications.
Distinct photoreceptor systems are responsible for mediating the effects of different light qualities on histone modifications.
Distinct photoreceptor systems mediate the effects of different light qualities on histone modifications.
Distinct photoreceptor systems are responsible for mediating the effects of different light qualities on histone modifications.
Distinct photoreceptor systems mediate the effects of different light qualities on histone modifications.
Distinct photoreceptor systems are responsible for mediating the effects of different light qualities on histone modifications.
Distinct photoreceptor systems mediate the effects of different light qualities on histone modifications.
Distinct photoreceptor systems are responsible for mediating the effects of different light qualities on histone modifications.
Variations in histone modifications may be an important physiological component of plant responses to changing light environments.
it is possible that variations in histone modifications are an important physiological component of plant responses to changing light environments
Variations in histone modifications may be an important physiological component of plant responses to changing light environments.
it is possible that variations in histone modifications are an important physiological component of plant responses to changing light environments
Variations in histone modifications may be an important physiological component of plant responses to changing light environments.
it is possible that variations in histone modifications are an important physiological component of plant responses to changing light environments
Variations in histone modifications may be an important physiological component of plant responses to changing light environments.
it is possible that variations in histone modifications are an important physiological component of plant responses to changing light environments
Variations in histone modifications may be an important physiological component of plant responses to changing light environments.
it is possible that variations in histone modifications are an important physiological component of plant responses to changing light environments
Variations in histone modifications may be an important physiological component of plant responses to changing light environments.
it is possible that variations in histone modifications are an important physiological component of plant responses to changing light environments
Variations in histone modifications may be an important physiological component of plant responses to changing light environments.
it is possible that variations in histone modifications are an important physiological component of plant responses to changing light environments
The examined histone modifications and gene transcription were cooperatively regulated in response to changing light environments.
We observed that the histone modifications examined and gene transcription were cooperatively regulated in response to changing light environments.
The examined histone modifications and gene transcription were cooperatively regulated in response to changing light environments.
We observed that the histone modifications examined and gene transcription were cooperatively regulated in response to changing light environments.
The examined histone modifications and gene transcription were cooperatively regulated in response to changing light environments.
We observed that the histone modifications examined and gene transcription were cooperatively regulated in response to changing light environments.
The examined histone modifications and gene transcription were cooperatively regulated in response to changing light environments.
We observed that the histone modifications examined and gene transcription were cooperatively regulated in response to changing light environments.
The examined histone modifications and gene transcription were cooperatively regulated in response to changing light environments.
We observed that the histone modifications examined and gene transcription were cooperatively regulated in response to changing light environments.
The examined histone modifications and gene transcription were cooperatively regulated in response to changing light environments.
We observed that the histone modifications examined and gene transcription were cooperatively regulated in response to changing light environments.
The examined histone modifications and gene transcription were cooperatively regulated in response to changing light environments.
We observed that the histone modifications examined and gene transcription were cooperatively regulated in response to changing light environments.
H3K9ac patterns are set up very early and are relatively stable during Arabidopsis seedling development.
Using H3K9ac as an example, our analysis indicated that histone modification patterns are set up very early and are relatively stable during Arabidopsis (Arabidopsis thaliana) seedling development.
H3K9ac patterns are set up very early and are relatively stable during Arabidopsis seedling development.
Using H3K9ac as an example, our analysis indicated that histone modification patterns are set up very early and are relatively stable during Arabidopsis (Arabidopsis thaliana) seedling development.
H3K9ac patterns are set up very early and are relatively stable during Arabidopsis seedling development.
Using H3K9ac as an example, our analysis indicated that histone modification patterns are set up very early and are relatively stable during Arabidopsis (Arabidopsis thaliana) seedling development.
H3K9ac patterns are set up very early and are relatively stable during Arabidopsis seedling development.
Using H3K9ac as an example, our analysis indicated that histone modification patterns are set up very early and are relatively stable during Arabidopsis (Arabidopsis thaliana) seedling development.
H3K9ac patterns are set up very early and are relatively stable during Arabidopsis seedling development.
Using H3K9ac as an example, our analysis indicated that histone modification patterns are set up very early and are relatively stable during Arabidopsis (Arabidopsis thaliana) seedling development.
H3K9ac patterns are set up very early and are relatively stable during Arabidopsis seedling development.
Using H3K9ac as an example, our analysis indicated that histone modification patterns are set up very early and are relatively stable during Arabidopsis (Arabidopsis thaliana) seedling development.
H3K9ac patterns are set up very early and are relatively stable during Arabidopsis seedling development.
Using H3K9ac as an example, our analysis indicated that histone modification patterns are set up very early and are relatively stable during Arabidopsis (Arabidopsis thaliana) seedling development.
Approval Evidence
1 source4 linked approval claimsfirst-pass slug h3k27me3
four selected histone modifications (H3K4me3, H3K9ac, H3K9me2, and H3K27me3)
Source:
functional rolesupports
Light-regulated changes in histone modifications may be an intricate part of light-controlled gene transcription.
our data suggest that light-regulated changes in histone modifications might be an intricate part of light-controlled gene transcription
Source:
mechanistic involvementsupports
Distinct photoreceptor systems mediate the effects of different light qualities on histone modifications.
Distinct photoreceptor systems are responsible for mediating the effects of different light qualities on histone modifications.
Source:
physiological relevancesupports
Variations in histone modifications may be an important physiological component of plant responses to changing light environments.
it is possible that variations in histone modifications are an important physiological component of plant responses to changing light environments
Source:
regulatory relationshipsupports
The examined histone modifications and gene transcription were cooperatively regulated in response to changing light environments.
We observed that the histone modifications examined and gene transcription were cooperatively regulated in response to changing light environments.
Source:
Comparisons
Source-backed strengths
The cited work places H3K27me3 within a comparative framework alongside H3K4me3, H3K9ac, and H3K9me2, enabling analysis of cooperative chromatin responses to light. Evidence also indicates that distinct photoreceptor systems mediate effects of different light qualities on histone modifications, supporting physiological relevance in plant light responses.
Ranked Citations
- 1.