Source 1review2015Annual Review of Biochemistry
Toolkit/high-throughput sequencing studies for alternative mRNA isoform detection
high-throughput sequencing studies for alternative mRNA isoform detection
Also known as: high-throughput sequencing
Taxonomy: Technique Branch / Method. Workflows sit above the mechanism and technique branches rather than replacing them.
Summary
Recent high-throughput sequencing studies indicate that 100% of human genes produce at least two alternative mRNA isoforms.
Usefulness & Problems
No literature-backed usefulness or problem-fit explainer has been materialized for this record yet.
Taxonomy & Function
Primary hierarchy
Technique Branch
Method: A concrete method used to build, optimize, or evolve an engineered system.
Techniques
Sequence VerificationTarget processes
No target processes tagged yet.
Validation
Cell-freeBacteriaMammalianMouseHumanTherapeuticIndep. Replication
Supporting Sources
Ranked Claims
Recent high-throughput sequencing studies indicate that human genes broadly produce multiple alternative mRNA isoforms, with the abstract stating that 100% of human genes produce at least two isoforms.
human genes with at least two alternative mRNA isoforms 100 %
Mechanistic understanding of splicing makes the spliceosome an attractive target for small-molecule, antisense, and genome-editing therapeutic interventions.
Approval Evidence
1 source1 linked approval claimfirst-pass slug high-throughput-sequencing-studies-for-alternative-mrna-isoform-detection
Recent high-throughput sequencing studies indicate that 100% of human genes produce at least two alternative mRNA isoforms.
Source:
prevalence summarysupports
Recent high-throughput sequencing studies indicate that human genes broadly produce multiple alternative mRNA isoforms, with the abstract stating that 100% of human genes produce at least two isoforms.
Source:
Comparisons
No literature-backed comparison notes have been materialized for this record yet.
Ranked Citations
- 1.