Source 1review2022Frontiers in Bioengineering and Biotechnology
Toolkit/in silico feedback control strategies
in silico feedback control strategies
Also known as: computer-controlled living systems, feedback control
Taxonomy: Technique Branch / Method. Workflows sit above the mechanism and technique branches rather than replacing them.
Summary
In silico feedback control strategies are computationally implemented control schemes coupled to optogenetic measurement and light stimulation platforms. They are used to create computer-controlled living systems through automated measurement and stimulation workflows.
Usefulness & Problems
Why this is useful
These strategies are useful for closing the loop between biological measurement and optical actuation in living systems. The cited review indicates that they operate across optogenetic platforms spanning different cell types and culture volumes, from single-cell stimulation to whole-culture illumination.
Source:
we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination
Problem solved
They address the problem of implementing real-time control over living systems using automated experimental platforms. Specifically, the review states that automated measurement and stimulation schemes enabled feedback control strategies in optogenetic systems.
Source:
we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination
Taxonomy & Function
Primary hierarchy
Technique Branch
Method: A concrete method used to build, optimize, or evolve an engineered system.
Techniques
Computational DesignTarget processes
No target processes tagged yet.
Input: Light
Implementation Constraints
Implementation requires an optogenetic platform with automated measurement and light-based stimulation capabilities. The supplied evidence supports use across different cell types and culture volumes, but it does not specify hardware configurations, genetic constructs, wavelengths, or software architectures.
The provided evidence is limited to a review-level statement that such strategies have been enabled by automated optogenetic platforms. No specific control algorithms, performance metrics, or comparative validation data are provided in the supplied evidence.
Validation
Cell-freeBacteriaMammalianMouseHumanTherapeuticIndep. Replication
Supporting Sources
Ranked Claims
Optogenetic experiment platform designs in the review span different cell types and culture volumes, from single-cell stimulation to whole-culture illumination.
we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination
Optogenetic experiment platform designs in the review span different cell types and culture volumes, from single-cell stimulation to whole-culture illumination.
we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination
Optogenetic experiment platform designs in the review span different cell types and culture volumes, from single-cell stimulation to whole-culture illumination.
we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination
Optogenetic experiment platform designs in the review span different cell types and culture volumes, from single-cell stimulation to whole-culture illumination.
we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination
Optogenetic experiment platform designs in the review span different cell types and culture volumes, from single-cell stimulation to whole-culture illumination.
we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination
Optogenetic experiment platform designs in the review span different cell types and culture volumes, from single-cell stimulation to whole-culture illumination.
we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination
Optogenetic experiment platform designs in the review span different cell types and culture volumes, from single-cell stimulation to whole-culture illumination.
we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination
Automated measurement and stimulation schemes on optogenetic platforms have enabled implementation of in silico feedback control strategies for computer-controlled living systems.
The development of automated measurement and stimulation schemes on these platforms has enabled researchers to implement various in silico feedback control strategies to achieve computer-controlled living systems
Automated measurement and stimulation schemes on optogenetic platforms have enabled implementation of in silico feedback control strategies for computer-controlled living systems.
The development of automated measurement and stimulation schemes on these platforms has enabled researchers to implement various in silico feedback control strategies to achieve computer-controlled living systems
Automated measurement and stimulation schemes on optogenetic platforms have enabled implementation of in silico feedback control strategies for computer-controlled living systems.
The development of automated measurement and stimulation schemes on these platforms has enabled researchers to implement various in silico feedback control strategies to achieve computer-controlled living systems
Automated measurement and stimulation schemes on optogenetic platforms have enabled implementation of in silico feedback control strategies for computer-controlled living systems.
The development of automated measurement and stimulation schemes on these platforms has enabled researchers to implement various in silico feedback control strategies to achieve computer-controlled living systems
Automated measurement and stimulation schemes on optogenetic platforms have enabled implementation of in silico feedback control strategies for computer-controlled living systems.
The development of automated measurement and stimulation schemes on these platforms has enabled researchers to implement various in silico feedback control strategies to achieve computer-controlled living systems
Automated measurement and stimulation schemes on optogenetic platforms have enabled implementation of in silico feedback control strategies for computer-controlled living systems.
The development of automated measurement and stimulation schemes on these platforms has enabled researchers to implement various in silico feedback control strategies to achieve computer-controlled living systems
Automated measurement and stimulation schemes on optogenetic platforms have enabled implementation of in silico feedback control strategies for computer-controlled living systems.
The development of automated measurement and stimulation schemes on these platforms has enabled researchers to implement various in silico feedback control strategies to achieve computer-controlled living systems
Emerging optogenetic applications require light delivery that is consistent, reproducible, and regulated according to application needs.
Emerging optogenetic applications entail a consistent, reproducible, and regulated delivery of light adapted to the application requirement.
Emerging optogenetic applications require light delivery that is consistent, reproducible, and regulated according to application needs.
Emerging optogenetic applications entail a consistent, reproducible, and regulated delivery of light adapted to the application requirement.
Emerging optogenetic applications require light delivery that is consistent, reproducible, and regulated according to application needs.
Emerging optogenetic applications entail a consistent, reproducible, and regulated delivery of light adapted to the application requirement.
Emerging optogenetic applications require light delivery that is consistent, reproducible, and regulated according to application needs.
Emerging optogenetic applications entail a consistent, reproducible, and regulated delivery of light adapted to the application requirement.
Emerging optogenetic applications require light delivery that is consistent, reproducible, and regulated according to application needs.
Emerging optogenetic applications entail a consistent, reproducible, and regulated delivery of light adapted to the application requirement.
Emerging optogenetic applications require light delivery that is consistent, reproducible, and regulated according to application needs.
Emerging optogenetic applications entail a consistent, reproducible, and regulated delivery of light adapted to the application requirement.
Emerging optogenetic applications require light delivery that is consistent, reproducible, and regulated according to application needs.
Emerging optogenetic applications entail a consistent, reproducible, and regulated delivery of light adapted to the application requirement.
The review covers optogenetic stimulation platform designs ranging from simple illumination set-ups to microscopy, microtiter plate, and bioreactor designs, each with advantages and disadvantages.
we explore the evolution of light-induction hardware-software platforms from simple illumination set-ups to sophisticated microscopy, microtiter plate and bioreactor designs, and discuss their respective advantages and disadvantages
The review covers optogenetic stimulation platform designs ranging from simple illumination set-ups to microscopy, microtiter plate, and bioreactor designs, each with advantages and disadvantages.
we explore the evolution of light-induction hardware-software platforms from simple illumination set-ups to sophisticated microscopy, microtiter plate and bioreactor designs, and discuss their respective advantages and disadvantages
The review covers optogenetic stimulation platform designs ranging from simple illumination set-ups to microscopy, microtiter plate, and bioreactor designs, each with advantages and disadvantages.
we explore the evolution of light-induction hardware-software platforms from simple illumination set-ups to sophisticated microscopy, microtiter plate and bioreactor designs, and discuss their respective advantages and disadvantages
The review covers optogenetic stimulation platform designs ranging from simple illumination set-ups to microscopy, microtiter plate, and bioreactor designs, each with advantages and disadvantages.
we explore the evolution of light-induction hardware-software platforms from simple illumination set-ups to sophisticated microscopy, microtiter plate and bioreactor designs, and discuss their respective advantages and disadvantages
The review covers optogenetic stimulation platform designs ranging from simple illumination set-ups to microscopy, microtiter plate, and bioreactor designs, each with advantages and disadvantages.
we explore the evolution of light-induction hardware-software platforms from simple illumination set-ups to sophisticated microscopy, microtiter plate and bioreactor designs, and discuss their respective advantages and disadvantages
The review covers optogenetic stimulation platform designs ranging from simple illumination set-ups to microscopy, microtiter plate, and bioreactor designs, each with advantages and disadvantages.
we explore the evolution of light-induction hardware-software platforms from simple illumination set-ups to sophisticated microscopy, microtiter plate and bioreactor designs, and discuss their respective advantages and disadvantages
The review covers optogenetic stimulation platform designs ranging from simple illumination set-ups to microscopy, microtiter plate, and bioreactor designs, each with advantages and disadvantages.
we explore the evolution of light-induction hardware-software platforms from simple illumination set-ups to sophisticated microscopy, microtiter plate and bioreactor designs, and discuss their respective advantages and disadvantages
Suitable light stimulation platforms are required to stimulate synthetic optogenetic constructs in biological systems.
Light stimulation of a synthetic optogenetic construct in a given biological species can only be achieved via a suitable light stimulation platform.
Suitable light stimulation platforms are required to stimulate synthetic optogenetic constructs in biological systems.
Light stimulation of a synthetic optogenetic construct in a given biological species can only be achieved via a suitable light stimulation platform.
Suitable light stimulation platforms are required to stimulate synthetic optogenetic constructs in biological systems.
Light stimulation of a synthetic optogenetic construct in a given biological species can only be achieved via a suitable light stimulation platform.
Suitable light stimulation platforms are required to stimulate synthetic optogenetic constructs in biological systems.
Light stimulation of a synthetic optogenetic construct in a given biological species can only be achieved via a suitable light stimulation platform.
Suitable light stimulation platforms are required to stimulate synthetic optogenetic constructs in biological systems.
Light stimulation of a synthetic optogenetic construct in a given biological species can only be achieved via a suitable light stimulation platform.
Suitable light stimulation platforms are required to stimulate synthetic optogenetic constructs in biological systems.
Light stimulation of a synthetic optogenetic construct in a given biological species can only be achieved via a suitable light stimulation platform.
Suitable light stimulation platforms are required to stimulate synthetic optogenetic constructs in biological systems.
Light stimulation of a synthetic optogenetic construct in a given biological species can only be achieved via a suitable light stimulation platform.
Approval Evidence
1 source1 linked approval claimfirst-pass slug in-silico-feedback-control-strategies
The development of automated measurement and stimulation schemes on these platforms has enabled researchers to implement various in silico feedback control strategies to achieve computer-controlled living systems
Source:
automation enables controlsupports
Automated measurement and stimulation schemes on optogenetic platforms have enabled implementation of in silico feedback control strategies for computer-controlled living systems.
The development of automated measurement and stimulation schemes on these platforms has enabled researchers to implement various in silico feedback control strategies to achieve computer-controlled living systems
Source:
Comparisons
Source-backed strengths
A key strength is compatibility with automated optogenetic platforms that integrate measurement and stimulation. The reviewed platform designs span multiple biological contexts and scales, including different cell types and culture volumes from single cells to whole cultures.
Ranked Citations
- 1.