Toolkit/light-induction hardware-software platforms

light-induction hardware-software platforms

Delivery Strategy·Research·Since 2022

Also known as: illumination set-ups, light stimulation platform

Taxonomy: Mechanism Branch / Architecture. Workflows sit above the mechanism and technique branches rather than replacing them.

Summary

Light-induction hardware-software platforms are optogenetic delivery systems that provide controlled illumination using formats ranging from simple illumination set-ups to microscopy, microtiter plate, and bioreactor designs. They are used to stimulate biological systems with light, and automated implementations can support computer-controlled experiments with in silico feedback control.

Usefulness & Problems

Why this is useful

These platforms are useful because they extend optogenetic stimulation across experimental scales, from single-cell stimulation to whole-culture illumination and across different cell types and culture volumes. Automated measurement and stimulation schemes further enable computer-controlled living systems through feedback-based experimental control.

Source:

we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination

Problem solved

They address the practical challenge of delivering controlled light stimulation in diverse biological formats and scales. They also help solve the systems-engineering problem of coupling optical stimulation with automated measurement for in silico feedback control.

Source:

we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination

Taxonomy & Function

Primary hierarchy

Mechanism Branch

Architecture: A delivery strategy grouped with the mechanism branch because it determines how a system is instantiated and deployed in context.

Target processes

No target processes tagged yet.

Input: Light

Implementation Constraints

Implementation formats mentioned in the evidence include simple illumination set-ups, microscopy systems, microtiter plate devices, and bioreactor designs. The supplied evidence supports light as the input modality and indicates that automated measurement-stimulation integration is required for in silico feedback control, but it does not specify wavelengths, optical components, software architecture, or biological host requirements.

The provided evidence is from a review-level description and does not report specific quantitative performance metrics such as irradiance range, temporal resolution, wavelength coverage, or control accuracy. Independent head-to-head validation, standardized benchmarks, and construct-specific implementation details are not provided in the supplied evidence.

Validation

Cell-freeBacteriaMammalianMouseHumanTherapeuticIndep. Replication

Supporting Sources

Ranked Claims

Claim 1application spansupports2022Source 1needs review

Optogenetic experiment platform designs in the review span different cell types and culture volumes, from single-cell stimulation to whole-culture illumination.

we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination
Claim 2application spansupports2022Source 1needs review

Optogenetic experiment platform designs in the review span different cell types and culture volumes, from single-cell stimulation to whole-culture illumination.

we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination
Claim 3application spansupports2022Source 1needs review

Optogenetic experiment platform designs in the review span different cell types and culture volumes, from single-cell stimulation to whole-culture illumination.

we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination
Claim 4application spansupports2022Source 1needs review

Optogenetic experiment platform designs in the review span different cell types and culture volumes, from single-cell stimulation to whole-culture illumination.

we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination
Claim 5application spansupports2022Source 1needs review

Optogenetic experiment platform designs in the review span different cell types and culture volumes, from single-cell stimulation to whole-culture illumination.

we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination
Claim 6application spansupports2022Source 1needs review

Optogenetic experiment platform designs in the review span different cell types and culture volumes, from single-cell stimulation to whole-culture illumination.

we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination
Claim 7application spansupports2022Source 1needs review

Optogenetic experiment platform designs in the review span different cell types and culture volumes, from single-cell stimulation to whole-culture illumination.

we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination
Claim 8automation enables controlsupports2022Source 1needs review

Automated measurement and stimulation schemes on optogenetic platforms have enabled implementation of in silico feedback control strategies for computer-controlled living systems.

The development of automated measurement and stimulation schemes on these platforms has enabled researchers to implement various in silico feedback control strategies to achieve computer-controlled living systems
Claim 9automation enables controlsupports2022Source 1needs review

Automated measurement and stimulation schemes on optogenetic platforms have enabled implementation of in silico feedback control strategies for computer-controlled living systems.

The development of automated measurement and stimulation schemes on these platforms has enabled researchers to implement various in silico feedback control strategies to achieve computer-controlled living systems
Claim 10automation enables controlsupports2022Source 1needs review

Automated measurement and stimulation schemes on optogenetic platforms have enabled implementation of in silico feedback control strategies for computer-controlled living systems.

The development of automated measurement and stimulation schemes on these platforms has enabled researchers to implement various in silico feedback control strategies to achieve computer-controlled living systems
Claim 11automation enables controlsupports2022Source 1needs review

Automated measurement and stimulation schemes on optogenetic platforms have enabled implementation of in silico feedback control strategies for computer-controlled living systems.

The development of automated measurement and stimulation schemes on these platforms has enabled researchers to implement various in silico feedback control strategies to achieve computer-controlled living systems
Claim 12automation enables controlsupports2022Source 1needs review

Automated measurement and stimulation schemes on optogenetic platforms have enabled implementation of in silico feedback control strategies for computer-controlled living systems.

The development of automated measurement and stimulation schemes on these platforms has enabled researchers to implement various in silico feedback control strategies to achieve computer-controlled living systems
Claim 13automation enables controlsupports2022Source 1needs review

Automated measurement and stimulation schemes on optogenetic platforms have enabled implementation of in silico feedback control strategies for computer-controlled living systems.

The development of automated measurement and stimulation schemes on these platforms has enabled researchers to implement various in silico feedback control strategies to achieve computer-controlled living systems
Claim 14automation enables controlsupports2022Source 1needs review

Automated measurement and stimulation schemes on optogenetic platforms have enabled implementation of in silico feedback control strategies for computer-controlled living systems.

The development of automated measurement and stimulation schemes on these platforms has enabled researchers to implement various in silico feedback control strategies to achieve computer-controlled living systems
Claim 15design requirementsupports2022Source 1needs review

Emerging optogenetic applications require light delivery that is consistent, reproducible, and regulated according to application needs.

Emerging optogenetic applications entail a consistent, reproducible, and regulated delivery of light adapted to the application requirement.
Claim 16design requirementsupports2022Source 1needs review

Emerging optogenetic applications require light delivery that is consistent, reproducible, and regulated according to application needs.

Emerging optogenetic applications entail a consistent, reproducible, and regulated delivery of light adapted to the application requirement.
Claim 17design requirementsupports2022Source 1needs review

Emerging optogenetic applications require light delivery that is consistent, reproducible, and regulated according to application needs.

Emerging optogenetic applications entail a consistent, reproducible, and regulated delivery of light adapted to the application requirement.
Claim 18design requirementsupports2022Source 1needs review

Emerging optogenetic applications require light delivery that is consistent, reproducible, and regulated according to application needs.

Emerging optogenetic applications entail a consistent, reproducible, and regulated delivery of light adapted to the application requirement.
Claim 19design requirementsupports2022Source 1needs review

Emerging optogenetic applications require light delivery that is consistent, reproducible, and regulated according to application needs.

Emerging optogenetic applications entail a consistent, reproducible, and regulated delivery of light adapted to the application requirement.
Claim 20design requirementsupports2022Source 1needs review

Emerging optogenetic applications require light delivery that is consistent, reproducible, and regulated according to application needs.

Emerging optogenetic applications entail a consistent, reproducible, and regulated delivery of light adapted to the application requirement.
Claim 21design requirementsupports2022Source 1needs review

Emerging optogenetic applications require light delivery that is consistent, reproducible, and regulated according to application needs.

Emerging optogenetic applications entail a consistent, reproducible, and regulated delivery of light adapted to the application requirement.
Claim 22platform rangesupports2022Source 1needs review

The review covers optogenetic stimulation platform designs ranging from simple illumination set-ups to microscopy, microtiter plate, and bioreactor designs, each with advantages and disadvantages.

we explore the evolution of light-induction hardware-software platforms from simple illumination set-ups to sophisticated microscopy, microtiter plate and bioreactor designs, and discuss their respective advantages and disadvantages
Claim 23platform rangesupports2022Source 1needs review

The review covers optogenetic stimulation platform designs ranging from simple illumination set-ups to microscopy, microtiter plate, and bioreactor designs, each with advantages and disadvantages.

we explore the evolution of light-induction hardware-software platforms from simple illumination set-ups to sophisticated microscopy, microtiter plate and bioreactor designs, and discuss their respective advantages and disadvantages
Claim 24platform rangesupports2022Source 1needs review

The review covers optogenetic stimulation platform designs ranging from simple illumination set-ups to microscopy, microtiter plate, and bioreactor designs, each with advantages and disadvantages.

we explore the evolution of light-induction hardware-software platforms from simple illumination set-ups to sophisticated microscopy, microtiter plate and bioreactor designs, and discuss their respective advantages and disadvantages
Claim 25platform rangesupports2022Source 1needs review

The review covers optogenetic stimulation platform designs ranging from simple illumination set-ups to microscopy, microtiter plate, and bioreactor designs, each with advantages and disadvantages.

we explore the evolution of light-induction hardware-software platforms from simple illumination set-ups to sophisticated microscopy, microtiter plate and bioreactor designs, and discuss their respective advantages and disadvantages
Claim 26platform rangesupports2022Source 1needs review

The review covers optogenetic stimulation platform designs ranging from simple illumination set-ups to microscopy, microtiter plate, and bioreactor designs, each with advantages and disadvantages.

we explore the evolution of light-induction hardware-software platforms from simple illumination set-ups to sophisticated microscopy, microtiter plate and bioreactor designs, and discuss their respective advantages and disadvantages
Claim 27platform rangesupports2022Source 1needs review

The review covers optogenetic stimulation platform designs ranging from simple illumination set-ups to microscopy, microtiter plate, and bioreactor designs, each with advantages and disadvantages.

we explore the evolution of light-induction hardware-software platforms from simple illumination set-ups to sophisticated microscopy, microtiter plate and bioreactor designs, and discuss their respective advantages and disadvantages
Claim 28platform rangesupports2022Source 1needs review

The review covers optogenetic stimulation platform designs ranging from simple illumination set-ups to microscopy, microtiter plate, and bioreactor designs, each with advantages and disadvantages.

we explore the evolution of light-induction hardware-software platforms from simple illumination set-ups to sophisticated microscopy, microtiter plate and bioreactor designs, and discuss their respective advantages and disadvantages
Claim 29review scope summarysupports2022Source 1needs review

Suitable light stimulation platforms are required to stimulate synthetic optogenetic constructs in biological systems.

Light stimulation of a synthetic optogenetic construct in a given biological species can only be achieved via a suitable light stimulation platform.
Claim 30review scope summarysupports2022Source 1needs review

Suitable light stimulation platforms are required to stimulate synthetic optogenetic constructs in biological systems.

Light stimulation of a synthetic optogenetic construct in a given biological species can only be achieved via a suitable light stimulation platform.
Claim 31review scope summarysupports2022Source 1needs review

Suitable light stimulation platforms are required to stimulate synthetic optogenetic constructs in biological systems.

Light stimulation of a synthetic optogenetic construct in a given biological species can only be achieved via a suitable light stimulation platform.
Claim 32review scope summarysupports2022Source 1needs review

Suitable light stimulation platforms are required to stimulate synthetic optogenetic constructs in biological systems.

Light stimulation of a synthetic optogenetic construct in a given biological species can only be achieved via a suitable light stimulation platform.
Claim 33review scope summarysupports2022Source 1needs review

Suitable light stimulation platforms are required to stimulate synthetic optogenetic constructs in biological systems.

Light stimulation of a synthetic optogenetic construct in a given biological species can only be achieved via a suitable light stimulation platform.
Claim 34review scope summarysupports2022Source 1needs review

Suitable light stimulation platforms are required to stimulate synthetic optogenetic constructs in biological systems.

Light stimulation of a synthetic optogenetic construct in a given biological species can only be achieved via a suitable light stimulation platform.
Claim 35review scope summarysupports2022Source 1needs review

Suitable light stimulation platforms are required to stimulate synthetic optogenetic constructs in biological systems.

Light stimulation of a synthetic optogenetic construct in a given biological species can only be achieved via a suitable light stimulation platform.

Approval Evidence

1 source5 linked approval claimsfirst-pass slug light-induction-hardware-software-platforms
In this review, we explore the evolution of light-induction hardware-software platforms from simple illumination set-ups to sophisticated microscopy, microtiter plate and bioreactor designs

Source:

application spansupports

Optogenetic experiment platform designs in the review span different cell types and culture volumes, from single-cell stimulation to whole-culture illumination.

we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination

Source:

automation enables controlsupports

Automated measurement and stimulation schemes on optogenetic platforms have enabled implementation of in silico feedback control strategies for computer-controlled living systems.

The development of automated measurement and stimulation schemes on these platforms has enabled researchers to implement various in silico feedback control strategies to achieve computer-controlled living systems

Source:

design requirementsupports

Emerging optogenetic applications require light delivery that is consistent, reproducible, and regulated according to application needs.

Emerging optogenetic applications entail a consistent, reproducible, and regulated delivery of light adapted to the application requirement.

Source:

platform rangesupports

The review covers optogenetic stimulation platform designs ranging from simple illumination set-ups to microscopy, microtiter plate, and bioreactor designs, each with advantages and disadvantages.

we explore the evolution of light-induction hardware-software platforms from simple illumination set-ups to sophisticated microscopy, microtiter plate and bioreactor designs, and discuss their respective advantages and disadvantages

Source:

review scope summarysupports

Suitable light stimulation platforms are required to stimulate synthetic optogenetic constructs in biological systems.

Light stimulation of a synthetic optogenetic construct in a given biological species can only be achieved via a suitable light stimulation platform.

Source:

Comparisons

Source-backed strengths

The cited review describes a broad design space, spanning simple illumination hardware through sophisticated microscopy, microtiter plate, and bioreactor platforms. Evidence also supports use across different cell types and culture volumes, including both single-cell and whole-culture illumination, and indicates that automated platforms can implement feedback control strategies.

Ranked Citations

  1. 1.
    StructuralSource 1Frontiers in Bioengineering and Biotechnology2022Claim 1Claim 2Claim 3

    Seeded from load plan for claim c1. Extracted from this source document.