Source 1primary paper2026MED
Toolkit/MGTbind
MGTbind
Also known as: molecular glue and ternary binding database
Taxonomy: Technique Branch / Method. Workflows sit above the mechanism and technique branches rather than replacing them.
Summary
we developed the molecular glue and ternary binding (MGTbind) database, providing comprehensive resources about ternary structures and experimental data for the coverage of MG-engaged interactome
Usefulness & Problems
No literature-backed usefulness or problem-fit explainer has been materialized for this record yet.
Taxonomy & Function
Primary hierarchy
Technique Branch
Method: A concrete computational method used to design, rank, or analyze an engineered system.
Target processes
degradationInput: Chemical
Validation
Cell-freeBacteriaMammalianMouseHumanTherapeuticIndep. Replication
Supporting Sources
Ranked Claims
MGTbind provides a fully functional web interface for global search and browsing and is freely accessible online.
MGTbind collects hierarchical binding affinity data to support exploration of cooperative binding mechanisms.
MGTbind contains 3093 manually curated molecular glues with chemical structures and physicochemical properties.
manually curated molecular glues 3093
MGTbind contains 3924 ternary interactions with bioactivity measurements including degradation capacities, in vitro biochemical activities, and cellular activities.
ternary interactions 3924
MGTbind integrates ternary complex structural data from the Protein Data Bank and from AlphaFold 3-generated models.
MGTbind is a database developed to provide comprehensive ternary structure and experimental data resources covering the molecular-glue-engaged interactome.
Approval Evidence
1 source6 linked approval claimsfirst-pass slug mgtbind
we developed the molecular glue and ternary binding (MGTbind) database, providing comprehensive resources about ternary structures and experimental data for the coverage of MG-engaged interactome
Source:
accessibilitysupports
MGTbind provides a fully functional web interface for global search and browsing and is freely accessible online.
Source:
database contentsupports
MGTbind collects hierarchical binding affinity data to support exploration of cooperative binding mechanisms.
Source:
database contentsupports
MGTbind contains 3093 manually curated molecular glues with chemical structures and physicochemical properties.
Source:
database contentsupports
MGTbind contains 3924 ternary interactions with bioactivity measurements including degradation capacities, in vitro biochemical activities, and cellular activities.
Source:
database contentsupports
MGTbind integrates ternary complex structural data from the Protein Data Bank and from AlphaFold 3-generated models.
Source:
resource descriptionsupports
MGTbind is a database developed to provide comprehensive ternary structure and experimental data resources covering the molecular-glue-engaged interactome.
Source:
Comparisons
No literature-backed comparison notes have been materialized for this record yet.
Ranked Citations
- 1.