Source 1review2022Frontiers in Bioengineering and Biotechnology
Toolkit/microscopy designs for optogenetic stimulation
microscopy designs for optogenetic stimulation
Also known as: microscopy designs
Taxonomy: Mechanism Branch / Architecture. Workflows sit above the mechanism and technique branches rather than replacing them.
Summary
Microscopy designs for optogenetic stimulation are light-delivery platform configurations that range from simple illumination set-ups to sophisticated microscopy, microtiter plate, and bioreactor designs. These platforms support optogenetic stimulation across experimental scales from single-cell stimulation to whole-culture illumination, and some incorporate automated measurement and stimulation for computer-controlled operation.
Usefulness & Problems
Why this is useful
These platform designs are useful because they provide optical stimulation infrastructure across diverse cell types and culture volumes. Automated measurement and stimulation schemes further enable in silico feedback control strategies for computer-controlled living systems.
Source:
we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination
Problem solved
This tool helps solve the practical problem of delivering optogenetic stimulation across very different experimental formats, from single-cell experiments to whole-culture illumination. It also addresses the need to couple stimulation with automated measurement so that feedback control can be implemented in living systems.
Source:
we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination
Taxonomy & Function
Primary hierarchy
Mechanism Branch
Architecture: A delivery strategy grouped with the mechanism branch because it determines how a system is instantiated and deployed in context.
Target processes
No target processes tagged yet.
Input: Light
Implementation Constraints
The available evidence indicates implementation formats ranging from simple illumination set-ups to microscopy, microtiter plate, and bioreactor designs. Automated measurement and stimulation are relevant practical features for platforms intended to support in silico feedback control, but the evidence does not specify hardware architectures or construct requirements.
The supplied evidence describes platform scope and automation capability but does not provide quantitative performance metrics such as spatial resolution, temporal precision, irradiance range, or throughput. It also does not specify particular optical components, wavelengths, or validation in named organisms or assays.
Validation
Cell-freeBacteriaMammalianMouseHumanTherapeuticIndep. Replication
Supporting Sources
Ranked Claims
Optogenetic experiment platform designs in the review span different cell types and culture volumes, from single-cell stimulation to whole-culture illumination.
we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination
Optogenetic experiment platform designs in the review span different cell types and culture volumes, from single-cell stimulation to whole-culture illumination.
we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination
Optogenetic experiment platform designs in the review span different cell types and culture volumes, from single-cell stimulation to whole-culture illumination.
we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination
Optogenetic experiment platform designs in the review span different cell types and culture volumes, from single-cell stimulation to whole-culture illumination.
we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination
Optogenetic experiment platform designs in the review span different cell types and culture volumes, from single-cell stimulation to whole-culture illumination.
we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination
Optogenetic experiment platform designs in the review span different cell types and culture volumes, from single-cell stimulation to whole-culture illumination.
we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination
Optogenetic experiment platform designs in the review span different cell types and culture volumes, from single-cell stimulation to whole-culture illumination.
we examine design approaches followed in performing optogenetic experiments spanning different cell types and culture volumes, with induction capabilities ranging from single cell stimulation to entire cell culture illumination
Automated measurement and stimulation schemes on optogenetic platforms have enabled implementation of in silico feedback control strategies for computer-controlled living systems.
The development of automated measurement and stimulation schemes on these platforms has enabled researchers to implement various in silico feedback control strategies to achieve computer-controlled living systems
Automated measurement and stimulation schemes on optogenetic platforms have enabled implementation of in silico feedback control strategies for computer-controlled living systems.
The development of automated measurement and stimulation schemes on these platforms has enabled researchers to implement various in silico feedback control strategies to achieve computer-controlled living systems
Automated measurement and stimulation schemes on optogenetic platforms have enabled implementation of in silico feedback control strategies for computer-controlled living systems.
The development of automated measurement and stimulation schemes on these platforms has enabled researchers to implement various in silico feedback control strategies to achieve computer-controlled living systems
Automated measurement and stimulation schemes on optogenetic platforms have enabled implementation of in silico feedback control strategies for computer-controlled living systems.
The development of automated measurement and stimulation schemes on these platforms has enabled researchers to implement various in silico feedback control strategies to achieve computer-controlled living systems
Automated measurement and stimulation schemes on optogenetic platforms have enabled implementation of in silico feedback control strategies for computer-controlled living systems.
The development of automated measurement and stimulation schemes on these platforms has enabled researchers to implement various in silico feedback control strategies to achieve computer-controlled living systems
Automated measurement and stimulation schemes on optogenetic platforms have enabled implementation of in silico feedback control strategies for computer-controlled living systems.
The development of automated measurement and stimulation schemes on these platforms has enabled researchers to implement various in silico feedback control strategies to achieve computer-controlled living systems
Automated measurement and stimulation schemes on optogenetic platforms have enabled implementation of in silico feedback control strategies for computer-controlled living systems.
The development of automated measurement and stimulation schemes on these platforms has enabled researchers to implement various in silico feedback control strategies to achieve computer-controlled living systems
Emerging optogenetic applications require light delivery that is consistent, reproducible, and regulated according to application needs.
Emerging optogenetic applications entail a consistent, reproducible, and regulated delivery of light adapted to the application requirement.
Emerging optogenetic applications require light delivery that is consistent, reproducible, and regulated according to application needs.
Emerging optogenetic applications entail a consistent, reproducible, and regulated delivery of light adapted to the application requirement.
Emerging optogenetic applications require light delivery that is consistent, reproducible, and regulated according to application needs.
Emerging optogenetic applications entail a consistent, reproducible, and regulated delivery of light adapted to the application requirement.
Emerging optogenetic applications require light delivery that is consistent, reproducible, and regulated according to application needs.
Emerging optogenetic applications entail a consistent, reproducible, and regulated delivery of light adapted to the application requirement.
Emerging optogenetic applications require light delivery that is consistent, reproducible, and regulated according to application needs.
Emerging optogenetic applications entail a consistent, reproducible, and regulated delivery of light adapted to the application requirement.
Emerging optogenetic applications require light delivery that is consistent, reproducible, and regulated according to application needs.
Emerging optogenetic applications entail a consistent, reproducible, and regulated delivery of light adapted to the application requirement.
Emerging optogenetic applications require light delivery that is consistent, reproducible, and regulated according to application needs.
Emerging optogenetic applications entail a consistent, reproducible, and regulated delivery of light adapted to the application requirement.
The review covers optogenetic stimulation platform designs ranging from simple illumination set-ups to microscopy, microtiter plate, and bioreactor designs, each with advantages and disadvantages.
we explore the evolution of light-induction hardware-software platforms from simple illumination set-ups to sophisticated microscopy, microtiter plate and bioreactor designs, and discuss their respective advantages and disadvantages
The review covers optogenetic stimulation platform designs ranging from simple illumination set-ups to microscopy, microtiter plate, and bioreactor designs, each with advantages and disadvantages.
we explore the evolution of light-induction hardware-software platforms from simple illumination set-ups to sophisticated microscopy, microtiter plate and bioreactor designs, and discuss their respective advantages and disadvantages
The review covers optogenetic stimulation platform designs ranging from simple illumination set-ups to microscopy, microtiter plate, and bioreactor designs, each with advantages and disadvantages.
we explore the evolution of light-induction hardware-software platforms from simple illumination set-ups to sophisticated microscopy, microtiter plate and bioreactor designs, and discuss their respective advantages and disadvantages
The review covers optogenetic stimulation platform designs ranging from simple illumination set-ups to microscopy, microtiter plate, and bioreactor designs, each with advantages and disadvantages.
we explore the evolution of light-induction hardware-software platforms from simple illumination set-ups to sophisticated microscopy, microtiter plate and bioreactor designs, and discuss their respective advantages and disadvantages
The review covers optogenetic stimulation platform designs ranging from simple illumination set-ups to microscopy, microtiter plate, and bioreactor designs, each with advantages and disadvantages.
we explore the evolution of light-induction hardware-software platforms from simple illumination set-ups to sophisticated microscopy, microtiter plate and bioreactor designs, and discuss their respective advantages and disadvantages
The review covers optogenetic stimulation platform designs ranging from simple illumination set-ups to microscopy, microtiter plate, and bioreactor designs, each with advantages and disadvantages.
we explore the evolution of light-induction hardware-software platforms from simple illumination set-ups to sophisticated microscopy, microtiter plate and bioreactor designs, and discuss their respective advantages and disadvantages
The review covers optogenetic stimulation platform designs ranging from simple illumination set-ups to microscopy, microtiter plate, and bioreactor designs, each with advantages and disadvantages.
we explore the evolution of light-induction hardware-software platforms from simple illumination set-ups to sophisticated microscopy, microtiter plate and bioreactor designs, and discuss their respective advantages and disadvantages
Suitable light stimulation platforms are required to stimulate synthetic optogenetic constructs in biological systems.
Light stimulation of a synthetic optogenetic construct in a given biological species can only be achieved via a suitable light stimulation platform.
Suitable light stimulation platforms are required to stimulate synthetic optogenetic constructs in biological systems.
Light stimulation of a synthetic optogenetic construct in a given biological species can only be achieved via a suitable light stimulation platform.
Suitable light stimulation platforms are required to stimulate synthetic optogenetic constructs in biological systems.
Light stimulation of a synthetic optogenetic construct in a given biological species can only be achieved via a suitable light stimulation platform.
Suitable light stimulation platforms are required to stimulate synthetic optogenetic constructs in biological systems.
Light stimulation of a synthetic optogenetic construct in a given biological species can only be achieved via a suitable light stimulation platform.
Suitable light stimulation platforms are required to stimulate synthetic optogenetic constructs in biological systems.
Light stimulation of a synthetic optogenetic construct in a given biological species can only be achieved via a suitable light stimulation platform.
Suitable light stimulation platforms are required to stimulate synthetic optogenetic constructs in biological systems.
Light stimulation of a synthetic optogenetic construct in a given biological species can only be achieved via a suitable light stimulation platform.
Suitable light stimulation platforms are required to stimulate synthetic optogenetic constructs in biological systems.
Light stimulation of a synthetic optogenetic construct in a given biological species can only be achieved via a suitable light stimulation platform.
Approval Evidence
1 source1 linked approval claimfirst-pass slug microscopy-designs-for-optogenetic-stimulation
from simple illumination set-ups to sophisticated microscopy, microtiter plate and bioreactor designs
Source:
platform rangesupports
The review covers optogenetic stimulation platform designs ranging from simple illumination set-ups to microscopy, microtiter plate, and bioreactor designs, each with advantages and disadvantages.
we explore the evolution of light-induction hardware-software platforms from simple illumination set-ups to sophisticated microscopy, microtiter plate and bioreactor designs, and discuss their respective advantages and disadvantages
Source:
Comparisons
Source-backed strengths
A key strength is the broad application span, with reported platform designs covering simple illumination set-ups as well as microscopy, microtiter plate, and bioreactor configurations. Another strength is compatibility with automated measurement and stimulation schemes that have enabled in silico feedback control.
Ranked Citations
- 1.