Source 1review2019Frontiers in Cellular Neuroscience
Toolkit/miniscopes
miniscopes
Also known as: miniature microscopes, miniaturized fluorescence microscopes
Taxonomy: Mechanism Branch / Architecture. Workflows sit above the mechanism and technique branches rather than replacing them.
Summary
The ability to simultaneously image the spatiotemporal activity signatures from many neurons during unrestrained vertebrate behaviors has become possible through the development of miniaturized fluorescence microscopes, or miniscopes, sufficiently light to be carried by small animals such as bats, birds and rodents.
Usefulness & Problems
No literature-backed usefulness or problem-fit explainer has been materialized for this record yet.
Taxonomy & Function
Primary hierarchy
Mechanism Branch
Architecture: A delivery strategy grouped with the mechanism branch because it determines how a system is instantiated and deployed in context.
Mechanisms
fluorescence imagingTarget processes
No target processes tagged yet.
Input: Light
Validation
Cell-freeBacteriaMammalianMouseHumanTherapeuticIndep. Replication
Supporting Sources
Ranked Claims
Novel miniscopes expand the toolset for affordable probing of neural circuit function during naturalistic behaviors.
These novel miniscopes will further expand the toolset of those seeking affordable methods to probe neural circuit function during naturalistic behaviors.
Open-source initiatives have broadened adoption of miniscopes in the neuroscience community.
More recently, open-source initiatives have led to an even broader adoption of miniscopes in the neuroscience community.
Miniscopes have been used to study neural circuits underlying song vocalization, action sequencing, head-direction tuning, spatial memory encoding, and sleep.
Miniscopes have permitted the study of circuits underlying song vocalization, action sequencing, head-direction tuning, spatial memory encoding and sleep to name a few.
Miniscopes enable simultaneous imaging of spatiotemporal activity signatures from many neurons during unrestrained vertebrate behaviors.
The ability to simultaneously image the spatiotemporal activity signatures from many neurons during unrestrained vertebrate behaviors has become possible through the development of miniaturized fluorescence microscopes, or miniscopes
Open-source miniscope designs allow rapid modification and extension of function, enabling capabilities such as wireless recording, concurrent electrophysiology and imaging, two-color fluorescence detection, simultaneous optical actuation and read-out, and wide-field or volumetric light-field imaging.
Open-source designs allow for rapid modification and extension of their function, which has resulted in a new generation of miniscopes that now permit wire-free or wireless recording, concurrent electrophysiology and imaging, two-color fluorescence detection, simultaneous optical actuation and read-out as well as wide-field and volumetric light-field imaging.
Approval Evidence
1 source5 linked approval claimsfirst-pass slug miniscopes
The ability to simultaneously image the spatiotemporal activity signatures from many neurons during unrestrained vertebrate behaviors has become possible through the development of miniaturized fluorescence microscopes, or miniscopes, sufficiently light to be carried by small animals such as bats, birds and rodents.
Source:
accessibility summarysupports
Novel miniscopes expand the toolset for affordable probing of neural circuit function during naturalistic behaviors.
These novel miniscopes will further expand the toolset of those seeking affordable methods to probe neural circuit function during naturalistic behaviors.
Source:
adoption summarysupports
Open-source initiatives have broadened adoption of miniscopes in the neuroscience community.
More recently, open-source initiatives have led to an even broader adoption of miniscopes in the neuroscience community.
Source:
application scopesupports
Miniscopes have been used to study neural circuits underlying song vocalization, action sequencing, head-direction tuning, spatial memory encoding, and sleep.
Miniscopes have permitted the study of circuits underlying song vocalization, action sequencing, head-direction tuning, spatial memory encoding and sleep to name a few.
Source:
capability summarysupports
Miniscopes enable simultaneous imaging of spatiotemporal activity signatures from many neurons during unrestrained vertebrate behaviors.
The ability to simultaneously image the spatiotemporal activity signatures from many neurons during unrestrained vertebrate behaviors has become possible through the development of miniaturized fluorescence microscopes, or miniscopes
Source:
engineering extensibilitysupports
Open-source miniscope designs allow rapid modification and extension of function, enabling capabilities such as wireless recording, concurrent electrophysiology and imaging, two-color fluorescence detection, simultaneous optical actuation and read-out, and wide-field or volumetric light-field imaging.
Open-source designs allow for rapid modification and extension of their function, which has resulted in a new generation of miniscopes that now permit wire-free or wireless recording, concurrent electrophysiology and imaging, two-color fluorescence detection, simultaneous optical actuation and read-out as well as wide-field and volumetric light-field imaging.
Source:
Comparisons
No literature-backed comparison notes have been materialized for this record yet.
Ranked Citations
- 1.