Source 1review2020Advanced Science
Toolkit/NIR light-based photoregulation
NIR light-based photoregulation
Also known as: photoregulation
Taxonomy: Technique Branch / Method. Workflows sit above the mechanism and technique branches rather than replacing them.
Summary
NIR light-based photoregulation is an engineering approach that uses near-infrared light to sense and/or modulate specific cellular events in living systems. It is described as supporting real-time operation in deep tissues with subcellular accuracy.
Usefulness & Problems
Why this is useful
This approach is useful because it is described as enabling real-time monitoring or control of cellular events in deep tissues while retaining subcellular spatial precision. The cited review places its application domain in cancer theranostics, regenerative medicine, and neuroscience research.
Source:
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
Source:
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
Problem solved
It addresses the challenge of sensing or modulating defined cellular events within deep living tissues in real time. The supplied evidence specifically emphasizes deep-tissue access and subcellular accuracy as the problem context.
Source:
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
Source:
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
Problem links
The summary explicitly describes real-time modulation of specific cellular events in deep tissues using NIR light, which is relevant to the gap's modulation component. It could be a plausible route toward less invasive neural interfacing than conventional optical approaches, but the supplied evidence is not brain- or human-specific.
We Can’t Take High-Resolution Movies of or Intervene in Brain Computation at the Single Neuron Level
Gap mapView gapThe summary explicitly mentions real-time modulation of specific cellular events in deep tissues with subcellular accuracy, which is plausibly relevant to non-destructive intervention in vivo. It is a weaker match than direct neural tools because the supplied evidence is not brain- or neuron-specific.
Taxonomy & Function
Primary hierarchy
Technique Branch
Method: A concrete method used to build, optimize, or evolve an engineered system.
Mechanisms
photoregulationTechniques
No technique tags yet.
Target processes
No target processes tagged yet.
Input: Light
Implementation Constraints
cofactor dependency: cofactor requirement unknownencoding mode: genetically encodedimplementation constraint: context specific validationimplementation constraint: spectral hardware requirementoperating role: builder
The available evidence only establishes that the method uses near-infrared light as the input modality for imaging and photoregulation in living systems. No specific construct designs, cofactors, delivery methods, hardware parameters, or expression systems are provided in the supplied material.
The supplied evidence does not specify particular molecular actuators, wavelength ranges, quantitative performance metrics, or experimental benchmarks. It also does not provide direct comparative data, implementation constraints, or independent validation beyond the cited review.
Validation
Cell-freeBacteriaMammalianMouseHumanTherapeuticIndep. Replication
Supporting Sources
Ranked Claims
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
Approval Evidence
1 source2 linked approval claimsfirst-pass slug nir-light-based-photoregulation
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
Source:
application domainsupports
The review states that NIR light-based techniques have applications in cancer theranostics, regenerative medicine, and neuroscience research.
In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed.
Source:
application scopesupports
NIR light-based imaging and photoregulation strategies are described as enabling real-time sensing or modulation of specific cellular events in deep tissues with subcellular accuracy.
Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy.
Source:
Comparisons
Source-backed strengths
The reported strengths are real-time sensing and/or modulation of specific cellular events, operation in deep tissues, and subcellular accuracy. The review also indicates relevance across multiple biomedical areas, including cancer theranostics, regenerative medicine, and neuroscience research.
NIR light-based photoregulation and Method for efficient synthesis of phycocyanobilin in cultured mammalian cells address a similar problem space.
Shared frame: same top-level item type; same primary input modality: light
Strengths here: may avoid an exogenous cofactor requirement.
Compared with optogenetic
NIR light-based photoregulation and optogenetic address a similar problem space.
Shared frame: same top-level item type; same primary input modality: light
Compared with reversible optogenetic unmasking-masking of Ct residues
NIR light-based photoregulation and reversible optogenetic unmasking-masking of Ct residues address a similar problem space.
Shared frame: same top-level item type; same primary input modality: light
Ranked Citations
- 1.