Source 1review2018Stem Cells International
Toolkit/noncoding RNA manipulation
noncoding RNA manipulation
Taxonomy: Technique Branch / Method. Workflows sit above the mechanism and technique branches rather than replacing them.
Summary
Noncoding RNA manipulation is identified in a 2018 review as a CRISPR/Cas9-based epigenetic technique. The supplied evidence establishes only that it falls within the review’s scope and that CRISPR/Cas9 opened new routes into epigenetics.
Usefulness & Problems
Why this is useful
The available evidence supports a general role for CRISPR/Cas9 in enabling new approaches in epigenetics, with noncoding RNA manipulation listed as one such approach. No specific use case, assay context, or performance outcome for noncoding RNA manipulation is provided in the supplied material.
Problem solved
Based on the supplied review statements, this category addresses epigenetic investigation or intervention using CRISPR/Cas9. The specific scientific problem solved by noncoding RNA manipulation is not described in the provided evidence.
Taxonomy & Function
Primary hierarchy
Technique Branch
Method: A concrete method used to build, optimize, or evolve an engineered system.
Mechanisms
No mechanism tags yet.
Target processes
editingrecombinationselectionImplementation Constraints
The only implementation detail supported by the evidence is that this approach is framed as utilizing the CRISPR/Cas9 system. No construct architecture, Cas9 variant, guide RNA design, delivery method, or expression system is described.
The evidence is limited to review-level scope statements and does not define the molecular implementation, target noncoding RNA classes, or experimental results. No information is provided on efficiency, specificity, organismal context, or reproducibility.
Validation
Cell-freeBacteriaMammalianMouseHumanTherapeuticIndep. Replication
Supporting Sources
Ranked Claims
The emergence of CRISPR/Cas9 technology has provided new routes into the epigenetics field.
In recent years, the emergence of CRISPR/Cas9 technology has provided us with new routes to the epigenetic field.
The review covers CRISPR/Cas9-based epigenetic techniques including epigenome editing, temporal and spatial control of epigenetic effectors, noncoding RNA manipulation, chromatin in vivo imaging, and epigenetic element screening.
In this review, novel epigenetic techniques utilizing the CRISPR/Cas9 system are the main contents to be discussed, including epigenome editing, temporal and spatial control of epigenetic effectors, noncoding RNA manipulation, chromatin in vivo imaging, and epigenetic element screening.
The review covers CRISPR/Cas9-based epigenetic techniques including epigenome editing, temporal and spatial control of epigenetic effectors, noncoding RNA manipulation, chromatin in vivo imaging, and epigenetic element screening.
In this review, novel epigenetic techniques utilizing the CRISPR/Cas9 system are the main contents to be discussed, including epigenome editing, temporal and spatial control of epigenetic effectors, noncoding RNA manipulation, chromatin in vivo imaging, and epigenetic element screening.
The review covers CRISPR/Cas9-based epigenetic techniques including epigenome editing, temporal and spatial control of epigenetic effectors, noncoding RNA manipulation, chromatin in vivo imaging, and epigenetic element screening.
In this review, novel epigenetic techniques utilizing the CRISPR/Cas9 system are the main contents to be discussed, including epigenome editing, temporal and spatial control of epigenetic effectors, noncoding RNA manipulation, chromatin in vivo imaging, and epigenetic element screening.
The review covers CRISPR/Cas9-based epigenetic techniques including epigenome editing, temporal and spatial control of epigenetic effectors, noncoding RNA manipulation, chromatin in vivo imaging, and epigenetic element screening.
In this review, novel epigenetic techniques utilizing the CRISPR/Cas9 system are the main contents to be discussed, including epigenome editing, temporal and spatial control of epigenetic effectors, noncoding RNA manipulation, chromatin in vivo imaging, and epigenetic element screening.
The review covers CRISPR/Cas9-based epigenetic techniques including epigenome editing, temporal and spatial control of epigenetic effectors, noncoding RNA manipulation, chromatin in vivo imaging, and epigenetic element screening.
In this review, novel epigenetic techniques utilizing the CRISPR/Cas9 system are the main contents to be discussed, including epigenome editing, temporal and spatial control of epigenetic effectors, noncoding RNA manipulation, chromatin in vivo imaging, and epigenetic element screening.
The review covers CRISPR/Cas9-based epigenetic techniques including epigenome editing, temporal and spatial control of epigenetic effectors, noncoding RNA manipulation, chromatin in vivo imaging, and epigenetic element screening.
In this review, novel epigenetic techniques utilizing the CRISPR/Cas9 system are the main contents to be discussed, including epigenome editing, temporal and spatial control of epigenetic effectors, noncoding RNA manipulation, chromatin in vivo imaging, and epigenetic element screening.
The review covers CRISPR/Cas9-based epigenetic techniques including epigenome editing, temporal and spatial control of epigenetic effectors, noncoding RNA manipulation, chromatin in vivo imaging, and epigenetic element screening.
In this review, novel epigenetic techniques utilizing the CRISPR/Cas9 system are the main contents to be discussed, including epigenome editing, temporal and spatial control of epigenetic effectors, noncoding RNA manipulation, chromatin in vivo imaging, and epigenetic element screening.
Approval Evidence
1 source1 linked approval claimfirst-pass slug noncoding-rna-manipulation
In this review, novel epigenetic techniques utilizing the CRISPR/Cas9 system are the main contents to be discussed, including ... noncoding RNA manipulation...
Source:
review scopesupports
The review covers CRISPR/Cas9-based epigenetic techniques including epigenome editing, temporal and spatial control of epigenetic effectors, noncoding RNA manipulation, chromatin in vivo imaging, and epigenetic element screening.
In this review, novel epigenetic techniques utilizing the CRISPR/Cas9 system are the main contents to be discussed, including epigenome editing, temporal and spatial control of epigenetic effectors, noncoding RNA manipulation, chromatin in vivo imaging, and epigenetic element screening.
Source:
Comparisons
Source-backed strengths
A stated strength is its inclusion among novel epigenetic techniques enabled by the CRISPR/Cas9 system. No direct validation data, molecular targets, or comparative advantages for noncoding RNA manipulation are reported in the supplied evidence.
Ranked Citations
- 1.