Source 1review2019Chemical Communications
Toolkit/photoswitchable peptides
photoswitchable peptides
Also known as: photocontrollable peptides
Taxonomy: Mechanism Branch / Component. Workflows sit above the mechanism and technique branches rather than replacing them.
Summary
Photoswitchable peptides have been recognized for many years; however, their functional implementation in biological systems has only recently been achieved... These exciting proof-of-principle studies highlight the tremendous potential of photocontrollable peptides as optochemical tools for chemical biology and biomedicine.
Usefulness & Problems
No literature-backed usefulness or problem-fit explainer has been materialized for this record yet.
Taxonomy & Function
Primary hierarchy
Mechanism Branch
Component: A low-level protein part used inside a larger architecture that realizes a mechanism.
Mechanisms
light-induced conformational switchingphotoisomerizationprotein-protein interaction modulationTechniques
Structural CharacterizationTarget processes
No target processes tagged yet.
Input: Light
Validation
Cell-freeBacteriaMammalianMouseHumanTherapeuticIndep. Replication
Supporting Sources
Ranked Claims
Peptides are acknowledged as excellent modulators of protein-protein interactions and have been important in the emergence of photopharmacology.
Biological modulation by photoswitchable peptides is driven by structural changes associated with incorporated photoswitches.
Proof-of-principle studies indicate strong potential for photocontrollable peptides as optochemical tools for chemical biology and biomedicine.
Photoswitchable peptides have only recently achieved functional implementation in biological systems despite being recognized for many years.
Approval Evidence
1 source4 linked approval claimsfirst-pass slug photoswitchable-peptides
Photoswitchable peptides have been recognized for many years; however, their functional implementation in biological systems has only recently been achieved... These exciting proof-of-principle studies highlight the tremendous potential of photocontrollable peptides as optochemical tools for chemical biology and biomedicine.
Source:
capabilitysupports
Peptides are acknowledged as excellent modulators of protein-protein interactions and have been important in the emergence of photopharmacology.
Source:
mechanism summarysupports
Biological modulation by photoswitchable peptides is driven by structural changes associated with incorporated photoswitches.
Source:
potentialsupports
Proof-of-principle studies indicate strong potential for photocontrollable peptides as optochemical tools for chemical biology and biomedicine.
Source:
review summarysupports
Photoswitchable peptides have only recently achieved functional implementation in biological systems despite being recognized for many years.
Source:
Comparisons
No literature-backed comparison notes have been materialized for this record yet.
Ranked Citations
- 1.