Source 1review2019Neuropsychopharmacology
Toolkit/polysomnography
polysomnography
Taxonomy: Technique Branch / Method. Workflows sit above the mechanism and technique branches rather than replacing them.
Summary
The introduction of polysomnography into psychiatric research confirmed a disturbance of sleep continuity in patients with depression...
Usefulness & Problems
Why this is useful
Polysomnography is presented as the measurement approach that objectively characterized disturbed sleep continuity and altered sleep architecture in depression. The abstract specifically links it to reduced slow-wave sleep and REM disinhibition features.; objective characterization of sleep continuity and sleep architecture in depression; measurement of REM and slow-wave sleep abnormalities
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Polysomnography is presented as the measurement approach that objectively characterized disturbed sleep continuity and altered sleep architecture in depression. The abstract specifically links it to reduced slow-wave sleep and REM disinhibition features.
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objective characterization of sleep continuity and sleep architecture in depression
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measurement of REM and slow-wave sleep abnormalities
Problem solved
It solves the need for objective measurement of sleep abnormalities associated with depression rather than relying only on symptom reports.; provides objective sleep measurements in psychiatric research
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It solves the need for objective measurement of sleep abnormalities associated with depression rather than relying only on symptom reports.
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provides objective sleep measurements in psychiatric research
Problem links
provides objective sleep measurements in psychiatric research
LiteratureIt solves the need for objective measurement of sleep abnormalities associated with depression rather than relying only on symptom reports.
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It solves the need for objective measurement of sleep abnormalities associated with depression rather than relying only on symptom reports.
Taxonomy & Function
Primary hierarchy
Technique Branch
Method: A concrete measurement method used to characterize an engineered system.
Techniques
Functional AssayTarget processes
diagnosticrecombinationImplementation Constraints
cofactor dependency: cofactor requirement unknownencoding mode: genetically encodedimplementation constraint: context specific validationoperating role: sensor
The review only supports that this method requires polysomnographic recording in psychiatric research settings. Specific hardware details are not provided in the abstract.; requires polysomnographic sleep recording infrastructure
The abstract states that the resulting REM abnormalities did not ultimately serve as differential-diagnostic markers for depression subtypes.; sleep abnormalities identified by this approach did not fulfill hopes as differential-diagnostic markers for depression subtypes
Validation
Cell-freeBacteriaMammalianMouseHumanTherapeuticIndep. Replication
Supporting Sources
Ranked Claims
REM sleep abnormalities in depression did not fulfill initial hopes of serving as differential-diagnostic markers for depression subtypes.
Polysomnography in psychiatric research confirmed disturbed sleep continuity in patients with depression and revealed decreased slow-wave sleep together with REM disinhibition features including shortened REM latency, increased REM density, and increased total REM sleep time.
The Cholinergic REM Induction Test showed that REM sleep abnormalities can be mimicked by administration of cholinomimetic agents.
Chrono-medical timing of sleep deprivation and light exposure is described as an important research avenue because of positive effects on mood in depression.
Approval Evidence
1 source2 linked approval claimsfirst-pass slug polysomnography
The introduction of polysomnography into psychiatric research confirmed a disturbance of sleep continuity in patients with depression...
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diagnostic utilitycontradicts
REM sleep abnormalities in depression did not fulfill initial hopes of serving as differential-diagnostic markers for depression subtypes.
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measurement summarysupports
Polysomnography in psychiatric research confirmed disturbed sleep continuity in patients with depression and revealed decreased slow-wave sleep together with REM disinhibition features including shortened REM latency, increased REM density, and increased total REM sleep time.
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Comparisons
Source-stated alternatives
No direct alternative measurement modality is explicitly contrasted in the abstract.
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No direct alternative measurement modality is explicitly contrasted in the abstract.
Source-backed strengths
confirmed sleep continuity disturbance in patients with depression; revealed decreased slow-wave sleep and REM disinhibition features
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confirmed sleep continuity disturbance in patients with depression
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revealed decreased slow-wave sleep and REM disinhibition features
Compared with cell-free systems-based high-throughput screening
polysomnography and cell-free systems-based high-throughput screening address a similar problem space because they share diagnostic, recombination.
Shared frame: same top-level item type; shared target processes: diagnostic, recombination
Compared with spatial transcriptomics
polysomnography and spatial transcriptomics address a similar problem space because they share diagnostic, recombination.
Shared frame: same top-level item type; shared target processes: diagnostic, recombination
Relative tradeoffs: appears more independently replicated.
Compared with split-protein complementation assays
polysomnography and split-protein complementation assays address a similar problem space because they share diagnostic, recombination.
Shared frame: same top-level item type; shared target processes: diagnostic, recombination
Ranked Citations
- 1.