Source 1review2022International Journal of Molecular Sciences
Toolkit/probiotics
probiotics
Taxonomy: Mechanism Branch / Architecture. Workflows sit above the mechanism and technique branches rather than replacing them.
Summary
The importance of factors such as stress, mode of delivery, the role of probiotics, circadian clock system, diet, and occupational and environmental exposure in the relationship between the gut microbiota and brain function through bidirectional communication, described as "the microbiome-gut-brain axis", is especially underlined.
Usefulness & Problems
Why this is useful
Probiotics are presented as a microbiota-modulating intervention relevant to communication between the gut microbiota and brain function. The abstract treats them as one of the important factors shaping the microbiota–gut–brain axis.; modulating the gut microbiome in the context of human health research; microbiota-targeted intervention concepts relevant to gut–brain communication
Source:
Probiotics are presented as a microbiota-modulating intervention relevant to communication between the gut microbiota and brain function. The abstract treats them as one of the important factors shaping the microbiota–gut–brain axis.
Source:
modulating the gut microbiome in the context of human health research
Source:
microbiota-targeted intervention concepts relevant to gut–brain communication
Problem solved
They are discussed as a way to modulate the gut microbiome in research on health and psychiatric-disorder-related gut–brain interactions.; providing a microbiota-modulating intervention category discussed in relation to psychiatric disorders
Source:
They are discussed as a way to modulate the gut microbiome in research on health and psychiatric-disorder-related gut–brain interactions.
Source:
providing a microbiota-modulating intervention category discussed in relation to psychiatric disorders
Problem links
providing a microbiota-modulating intervention category discussed in relation to psychiatric disorders
LiteratureThey are discussed as a way to modulate the gut microbiome in research on health and psychiatric-disorder-related gut–brain interactions.
Source:
They are discussed as a way to modulate the gut microbiome in research on health and psychiatric-disorder-related gut–brain interactions.
Taxonomy & Function
Primary hierarchy
Mechanism Branch
Architecture: A reusable architecture pattern for arranging parts into an engineered system.
Mechanisms
microbiota modulationTechniques
No technique tags yet.
Target processes
No target processes tagged yet.
Implementation Constraints
cofactor dependency: cofactor requirement unknownencoding mode: genetically encodedimplementation constraint: context specific validationoperating role: actuator
Use of probiotics would require defined microbial preparations or formulations, but the abstract does not name any specific products or strains.; requires selection of specific probiotic organisms or formulations, which are not detailed in the provided evidence
The provided text does not show that probiotics solve any specific psychiatric disorder or mechanism on their own, and it does not provide comparative efficacy.; the abstract does not specify particular probiotic strains, formulations, or disorder-specific efficacy
Validation
Cell-freeBacteriaMammalianMouseHumanTherapeuticIndep. Replication
Supporting Sources
Ranked Claims
Probiotics are highlighted as an important factor in the relationship between gut microbiota and brain function within the microbiota–gut–brain axis.
Approval Evidence
1 source1 linked approval claimfirst-pass slug probiotics
The importance of factors such as stress, mode of delivery, the role of probiotics, circadian clock system, diet, and occupational and environmental exposure in the relationship between the gut microbiota and brain function through bidirectional communication, described as "the microbiome-gut-brain axis", is especially underlined.
Source:
intervention contextsupports
Probiotics are highlighted as an important factor in the relationship between gut microbiota and brain function within the microbiota–gut–brain axis.
Source:
Comparisons
Source-stated alternatives
The abstract also highlights other relevant factors and pathways, including diet, stress, circadian clock system, mode of delivery, endocrine mechanisms, immunological mechanisms, neurotransmitters, and bacterial metabolites.
Source:
The abstract also highlights other relevant factors and pathways, including diet, stress, circadian clock system, mode of delivery, endocrine mechanisms, immunological mechanisms, neurotransmitters, and bacterial metabolites.
Source-backed strengths
explicitly identified in the abstract as an important factor in the microbiota–gut–brain relationship
Source:
explicitly identified in the abstract as an important factor in the microbiota–gut–brain relationship
Ranked Citations
- 1.