Source 1review2016ACS Chemical Biology
Toolkit/protein-based dimerizing domains for Cas9 control
protein-based dimerizing domains for Cas9 control
Taxonomy: Mechanism Branch / Architecture. Workflows sit above the mechanism and technique branches rather than replacing them.
Summary
Here, we review recent advancements to modulate Cas9-mediated genome editing by engineering... protein-based dimerizing domains...
Usefulness & Problems
No literature-backed usefulness or problem-fit explainer has been materialized for this record yet.
Taxonomy & Function
Primary hierarchy
Mechanism Branch
Architecture: A composed arrangement of multiple parts that instantiates one or more mechanisms.
Mechanisms
HeterodimerizationTechniques
No technique tags yet.
Target processes
editingInput: Light
Validation
Cell-freeBacteriaMammalianMouseHumanTherapeuticIndep. Replication
Supporting Sources
Ranked Claims
The review covers split-Cas9 constructs, inteins, small molecules, protein-based dimerizing domains, and light-inducible systems as strategies to modulate Cas9-mediated genome editing.
Here, we review recent advancements to modulate Cas9-mediated genome editing by engineering split-Cas9 constructs, inteins, small molecules, protein-based dimerizing domains, and light-inducible systems.
Approval Evidence
1 source1 linked approval claimfirst-pass slug protein-based-dimerizing-domains-for-cas9-control
Here, we review recent advancements to modulate Cas9-mediated genome editing by engineering... protein-based dimerizing domains...
Source:
review scope statementsupports
The review covers split-Cas9 constructs, inteins, small molecules, protein-based dimerizing domains, and light-inducible systems as strategies to modulate Cas9-mediated genome editing.
Here, we review recent advancements to modulate Cas9-mediated genome editing by engineering split-Cas9 constructs, inteins, small molecules, protein-based dimerizing domains, and light-inducible systems.
Source:
Comparisons
No literature-backed comparison notes have been materialized for this record yet.
Ranked Citations
- 1.