Source 1review2022Current Opinion in Structural Biology
Toolkit/quantum chemical calculations
quantum chemical calculations
Taxonomy: Technique Branch / Method. Workflows sit above the mechanism and technique branches rather than replacing them.
Summary
Here we review recent progress in combining time-resolved crystallography at X-ray free electron lasers and quantum chemical calculations to study structural changes in photoenzymes, photosynthetic proteins, photoreceptors, and photoswitchable fluorescent proteins following photoexcitation.
Usefulness & Problems
No literature-backed usefulness or problem-fit explainer has been materialized for this record yet.
Published Workflows
Objective: Study structural changes and molecular mechanisms in light-sensitive proteins following photoexcitation by integrating experimental structural measurements with computational analysis.
Why it works: The review explicitly frames recent progress as coming from combining time-resolved crystallography at XFELs with quantum chemical calculations, implying complementary experimental and computational views of photoinduced structural dynamics.
photoexcitation-driven structural changetime-resolved crystallographyX-ray free electron laser measurementsquantum chemical calculations
Taxonomy & Function
Primary hierarchy
Technique Branch
Method: A concrete computational method used to design, rank, or analyze an engineered system.
Target processes
No target processes tagged yet.
Input: Light
Validation
Cell-freeBacteriaMammalianMouseHumanTherapeuticIndep. Replication
Supporting Sources
Ranked Claims
Structural dynamics underlying molecular mechanisms of light-sensitive proteins can be studied by a variety of experimental and computational biophysical techniques.
The structural dynamics underlying molecular mechanisms of light-sensitive proteins can be studied by a variety of experimental and computational biophysical techniques.
Recent progress has combined time-resolved crystallography at X-ray free electron lasers with quantum chemical calculations to study structural changes in light-sensitive proteins following photoexcitation.
Here we review recent progress in combining time-resolved crystallography at X-ray free electron lasers and quantum chemical calculations to study structural changes in photoenzymes, photosynthetic proteins, photoreceptors, and photoswitchable fluorescent proteins following photoexcitation.
Approval Evidence
1 source2 linked approval claimsfirst-pass slug quantum-chemical-calculations
Here we review recent progress in combining time-resolved crystallography at X-ray free electron lasers and quantum chemical calculations to study structural changes in photoenzymes, photosynthetic proteins, photoreceptors, and photoswitchable fluorescent proteins following photoexcitation.
Source:
capability summarysupports
Structural dynamics underlying molecular mechanisms of light-sensitive proteins can be studied by a variety of experimental and computational biophysical techniques.
The structural dynamics underlying molecular mechanisms of light-sensitive proteins can be studied by a variety of experimental and computational biophysical techniques.
Source:
review scope summarysupports
Recent progress has combined time-resolved crystallography at X-ray free electron lasers with quantum chemical calculations to study structural changes in light-sensitive proteins following photoexcitation.
Here we review recent progress in combining time-resolved crystallography at X-ray free electron lasers and quantum chemical calculations to study structural changes in photoenzymes, photosynthetic proteins, photoreceptors, and photoswitchable fluorescent proteins following photoexcitation.
Source:
Comparisons
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Ranked Citations
- 1.