Source 1review2015Photochemistry and Photobiology
Toolkit/UVR8
UVR8
Also known as: Arabidopsis thaliana UVR8, AtUVR8
Taxonomy: Mechanism Branch / Architecture. Workflows sit above the mechanism and technique branches rather than replacing them.
Summary
UVR8 is an Arabidopsis thaliana UV-B photoreceptor that senses solar UV-B light in the 280-315 nm range. It functions as a light-responsive multi-component switch through UV-B-induced dissociation of a UVR8 dimer.
Usefulness & Problems
Why this is useful
UVR8 provides a genetically encoded means to couple UV-B illumination to a defined protein-state change, namely conversion from a dimeric to a dissociated state. This makes it useful for studying and potentially harnessing UV-B-responsive signaling based on a native photoreceptor mechanism.
Problem solved
UVR8 addresses the problem of sensing and transducing UV-B light into a molecular switching event. Specifically, it provides a biological mechanism for detecting solar UV-B and converting that input into light-induced dimer dissociation.
Problem links
Need precise spatiotemporal control with light input
DerivedUVR8 is an Arabidopsis thaliana plant photoreceptor that senses solar UV-B light in the 280-315 nm range. It functions through UV-B-induced dissociation of a UVR8 dimer, making it a light-responsive multi-component switch.
Taxonomy & Function
Primary hierarchy
Mechanism Branch
Architecture: A composed arrangement of multiple parts that instantiates one or more mechanisms.
Mechanisms
HeterodimerizationHeterodimerizationHeterodimerizationlight-induced dimer dissociationlight-induced dimer dissociationTechniques
Structural CharacterizationTarget processes
No target processes tagged yet.
Input: Light
Implementation Constraints
cofactor dependency: cofactor requirement unknownencoding mode: genetically encodedimplementation constraint: context specific validationimplementation constraint: multi component delivery burdenimplementation constraint: spectral hardware requirementoperating role: actuatorswitch architecture: multi componentswitch architecture: recruitment
The evidence supports use of UV-B light in the 280-315 nm range as the activating input. Beyond its identity as an Arabidopsis thaliana photoreceptor that undergoes dimer dissociation, the supplied material does not specify cofactors, expression requirements, fusion architectures, or delivery considerations.
The supplied evidence is limited to a review-level description of UV-B perception and does not provide quantitative performance data such as kinetics, reversibility, dynamic range, or behavior in heterologous systems. No independent application-focused validation or construct-design guidance is provided in the supplied sources.
Validation
Cell-freeBacteriaMammalianMouseHumanTherapeuticIndep. Replication
Supporting Sources
Source 2review2017Journal of Experimental Neuroscience
Ranked Claims
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Approval Evidence
2 sources3 linked approval claimsfirst-pass slug uvr8
Explicitly supported in the supplied web research summary as a photoactivatable optogenetic system aligned with the review scope.
Source:
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation.
Source:
mechanism summarysupports
UVR8 mediates plant light responses to UV-B and perceives the signal through light-induced dimer dissociation.
UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation
Source:
review scope summarysupports
The review synthesizes spectroscopic, computational, and crystallographic studies aimed at understanding UV-B perception by UVR8 at the molecular level.
This review summarizes recent advances in spectroscopic, computational and crystallographic studies on UVR8 that are directed toward full understanding of UV-B perception at the molecular level.
Source:
structural summarysupports
Recent crystal structures of Arabidopsis thaliana UVR8 revealed clustering of UV-B-absorbing tryptophan pigments at the dimer interface and provide a framework for mechanistic investigation.
Two recent crystal structures of Arabidopsis thaliana UVR8 (AtUVR8) have revealed unusual clustering of UV-B-absorbing Trp pigments at the dimer interface and provided a structural framework for further mechanistic investigation.
Source:
Comparisons
Source-backed strengths
The available evidence identifies UVR8 as the only known plant photoreceptor that mediates light responses to UV-B in the 280-315 nm range. Its switching mechanism is defined at the molecular level as light-induced dimer dissociation, and the cited review indicates support from spectroscopic, computational, and crystallographic studies.
Compared with LightOn system
UVR8 and LightOn system address a similar problem space.
Shared frame: same top-level item type; shared mechanisms: heterodimerization; same primary input modality: light
Compared with photo-activatable Akt probe
UVR8 and photo-activatable Akt probe address a similar problem space.
Shared frame: same top-level item type; shared mechanisms: heterodimerization; same primary input modality: light
Compared with tandem-dimer nano (tdnano)
UVR8 and tandem-dimer nano (tdnano) address a similar problem space.
Shared frame: same top-level item type; shared mechanisms: heterodimerization; same primary input modality: light
Ranked Citations
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Extracted from this source document.