Browse the toolkit beneath workflows. The mechanism branch runs mechanism -> architecture -> component, while the technique branch runs from high-level approaches down to concrete methods.
2 items matching 1 filter
Mechanism Branch
Layer 1
Mechanisms
Top-level concepts: biophysical action modes such as heterodimerization, photocleavage, or RNA binding.
Layer 2
Architectures
Arrangements that realize or deploy mechanisms, including switches, construct patterns, and delivery strategies.
Layer 3
Components
Low-level parts and sequence-defined elements used inside architectures, including protein domains and RNA elements.
Technique Branch
Layer 1
Approaches
High-level engineering practices such as computational design, directed evolution, sequence verification, and functional assay.
Layer 2
Methods
Concrete methods used to design, build, verify, or characterize engineered systems.
Showing 1-2 of 2
Optogenetic control of apical constriction is an engineering method that uses light to drive apical constriction and thereby induce synthetic morphogenesis in mammalian tissues. The available evidence supports this method as a light-responsive approach for reshaping tissue architecture.
OptoShroom3 is an optogenetic multi-component switch developed for fast spatiotemporal control of apical constriction in mammalian epithelia. Illumination reduces the apical surface area of targeted epithelial cells and can induce synthetic tissue deformations and morphogenesis.