Browse the toolkit beneath workflows. The mechanism branch runs mechanism -> architecture -> component, while the technique branch runs from high-level approaches down to concrete methods.
3 items matching 1 filter
Mechanism Branch
Layer 1
Mechanisms
Top-level concepts: biophysical action modes such as heterodimerization, photocleavage, or RNA binding.
Layer 2
Architectures
Arrangements that realize or deploy mechanisms, including switches, construct patterns, and delivery strategies.
Layer 3
Components
Low-level parts and sequence-defined elements used inside architectures, including protein domains and RNA elements.
Technique Branch
Layer 1
Approaches
High-level engineering practices such as computational design, directed evolution, sequence verification, and functional assay.
Layer 2
Methods
Concrete methods used to design, build, verify, or characterize engineered systems.
Showing 1-3 of 3
Arabidopsis phototropins phot1 and phot2 are blue-light receptor proteins from Arabidopsis thaliana that optimize photosynthetic efficiency. Targeted mutagenesis of these photoreceptors can tune photocycle lifetime and thereby alter the duration of receptor activation in planta.
WC-1 is a LOV blue-light photoreceptor from the fungus Neurospora crassa that has been used with the partner photoreceptor VVD in the FUN-LOV optogenetic switch. In Saccharomyces cerevisiae, the WC-1/VVD pair mediates photon-regulated interaction to drive light-inducible transcriptional control and associated phenotypes such as flocculation.
Plant cryptochromes are blue-light photoreceptors from land plants and algae that act as multi-component light switches. They are described as signaling through a photoreaction centered on flavin adenine dinucleotide, with current models linking flavin reduction to dissociation of a C-terminal extension.