Browse the toolkit beneath workflows. The mechanism branch runs mechanism -> architecture -> component, while the technique branch runs from high-level approaches down to concrete methods.
4 items matching 1 filter
Mechanism Branch
Layer 1
Mechanisms
Top-level concepts: biophysical action modes such as heterodimerization, photocleavage, or RNA binding.
Layer 2
Architectures
Arrangements that realize or deploy mechanisms, including switches, construct patterns, and delivery strategies.
Layer 3
Components
Low-level parts and sequence-defined elements used inside architectures, including protein domains and RNA elements.
Technique Branch
Layer 1
Approaches
High-level engineering practices such as computational design, directed evolution, sequence verification, and functional assay.
Layer 2
Methods
Concrete methods used to design, build, verify, or characterize engineered systems.
Showing 1-4 of 4
LiCre is a single-chain light-inducible Cre recombinase optogenetic switch. The supplied evidence supports that blue light can activate Cre-dependent recombination outputs, including induction of antibiotic resistance gene expression in Escherichia coli.
Here, we describe the generation and validation of a transgenic CRF1-Cre-tdTomato rat.
The web research summary states that the review explicitly says a Kupffer-cell-specific Clec4f-Cre transgenic mouse line was used to study intrinsic and environmental factors in Kupffer-cell differentiation after depletion.
The supplied web research summary explicitly identifies DAT-Cre as a genetic targeting component used in selective dopamine-neuron stimulation and terminal-dynamics studies relevant to this review topic.