Toolkit Items

Browse the toolkit beneath workflows. The mechanism branch runs mechanism -> architecture -> component, while the technique branch runs from high-level approaches down to concrete methods.

18 items matching 1 filter

Mechanism Branch

Layer 1

Mechanisms

Top-level concepts: biophysical action modes such as heterodimerization, photocleavage, or RNA binding.

Layer 2

Architectures

Arrangements that realize or deploy mechanisms, including switches, construct patterns, and delivery strategies.

Layer 3

Components

Low-level parts and sequence-defined elements used inside architectures, including protein domains and RNA elements.

Technique Branch

Layer 1

Approaches

High-level engineering practices such as computational design, directed evolution, sequence verification, and functional assay.

Layer 2

Methods

Concrete methods used to design, build, verify, or characterize engineered systems.

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electrophysiological recording

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3D microelectrode arrays

Assay Method

Novel 3D microelectrode arrays permit high-resolution spatiotemporal electrophysiological signaling and recording to explore the capacity of brain organoids to recapitulate the molecular mechanisms of learning and memory formation and, ultimately, their computational potential.

CFBacMamMusHumTxRep
Ev 14Rep 9Pr 71

juxtacellular recording

Assay Method

Juxtacellular recording is an electrophysiological assay method identified as an emerging technique that can be combined with the optogenetic toolbox. In the cited epilepsy context, it is positioned as a recording approach used alongside light-driven perturbation to help identify cortical and hippocampal neuron subtypes altered in epileptic networks.

CFBacMamMusHumTxRep
Ev 20Rep 9Pr 59

in vivo electrophysiology

Assay Method

The supplied upstream summary states that the anchor PubMed abstract explicitly lists in vivo electrophysiology as a compatible tool for probing tolerance neurobiology.

CFBacMamMusHumTxRep
Ev 18Rep 9Pr 59
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