catalytically inactive NS3 protease
Protein DomainCatalytically inactive NS3 protease is a protein domain repurposed as a high-affinity binder for genetically encoded antiviral peptides. In the reported system, peptide-bound NS3 complexes are displaced by FDA-approved NS3-targeting drugs to chemically control transcription, cell signaling, split-protein complementation, and allosteric Cre recombinase regulation.