Browse the toolkit beneath workflows. The mechanism branch runs mechanism -> architecture -> component, while the technique branch runs from high-level approaches down to concrete methods.
2 items matching 1 filter
Mechanism Branch
Layer 1
Mechanisms
Top-level concepts: biophysical action modes such as heterodimerization, photocleavage, or RNA binding.
Layer 2
Architectures
Arrangements that realize or deploy mechanisms, including switches, construct patterns, and delivery strategies.
Layer 3
Components
Low-level parts and sequence-defined elements used inside architectures, including protein domains and RNA elements.
Technique Branch
Layer 1
Approaches
High-level engineering practices such as computational design, directed evolution, sequence verification, and functional assay.
Layer 2
Methods
Concrete methods used to design, build, verify, or characterize engineered systems.
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The 2D silicene-based nonviral vector, termed silicene-Cas9, is a NIR-II light-controlled CRISPR/Cas9 nanosystem built from 2D silicene nanosheets. It is designed to harness the photothermal-conversion capability of biosafe, biodegradable silicene for nonviral genome-editing delivery.
silicene-Cas9 is a NIR-II light-controlled CRISPR/Cas9 nanosystem built on biosafe, biodegradable 2D silicene nanosheets with photothermal-conversion capability. It is reported to mediate remote light-triggered TXNDC5 gene knockdown and to couple genome editing with tumor microenvironment reprogramming and augmented photonic tumor ablation.