Exendin-4 fused with anti-neonatal Fc receptor affibody
Construct PatternExendin-4 fused with an anti-neonatal Fc receptor affibody is a therapeutic fusion payload used in the ROEN red light-controlled probiotic system. In the cited murine study, this construct was released under optogenetic control in the gut to mediate gut-brain axis regulation and was evaluated in a Parkinson's disease mouse model after oral administration.