Mechanism Index
Mechanisms
Biophysical action modes, each summarized with the architectures, components, and enabled capabilities currently represented in the toolkit.
9 mechanisms
Translation Control
186 itemsPost-transcriptional regulation of mRNA translation rate or efficiency.
Heterodimerization
177 itemsTwo different proteins are brought together by a stimulus, enabling recruitment or complex formation.
Conformational Uncaging
104 itemsA stimulus triggers a structural change that exposes a previously hidden functional element.
Photocleavage
90 itemsLight breaks a covalent bond, irreversibly releasing a caged peptide or domain.
Degradation
87 itemsA stimulus triggers targeted degradation of a protein via the proteasome or other pathways.
Oligomerization
47 itemsA protein self-associates into multimers upon stimulation, enabling clustering or activation.
Membrane Recruitment
19 itemsA protein is recruited to a membrane surface (e.g. plasma membrane) by a stimulus.
DNA Binding
17 itemsA protein binds DNA in a stimulus-dependent manner to regulate gene expression.
RNA Binding
2 itemsA protein or RNA element binds RNA to control translation or stability.