Source 1review2018Frontiers in Plant Science
Toolkit/long non-coding RNA
long non-coding RNA
Also known as: lncRNA, lncRNAs
Taxonomy: Mechanism Branch / Component. Workflows sit above the mechanism and technique branches rather than replacing them.
Summary
Long non-coding RNAs (lncRNAs) are non-protein-coding RNA elements within the broader non-coding RNA landscape. In plants, available reports indicate that lncRNAs participate in light-dependent processes including photomorphogenesis, cotyledon greening, and photoperiod-regulated flowering.
Usefulness & Problems
Why this is useful
lncRNAs are useful as endogenous regulatory RNA elements associated with plant light-response pathways. The cited evidence supports their relevance for studying how non-coding RNAs contribute to developmental responses controlled by light.
Problem solved
This class of RNA helps address the problem of identifying non-protein-coding regulators involved in plant light-dependent development. The available evidence specifically links lncRNAs to photomorphogenesis, cotyledon greening, and photoperiod-regulated flowering.
Problem links
Need precise spatiotemporal control with light input
DerivedLong non-coding RNAs (lncRNAs) are non-protein-coding RNA elements within the broader non-coding RNA landscape. In plants, available reports indicate that lncRNAs participate in light-dependent processes including photomorphogenesis, cotyledon greening, and photoperiod-regulated flowering.
Taxonomy & Function
Primary hierarchy
Mechanism Branch
Component: A low-level RNA part used inside a larger architecture that realizes a mechanism.
Techniques
Sequence VerificationTarget processes
No target processes tagged yet.
Input: Light
Implementation Constraints
cofactor dependency: cofactor requirement unknownencoding mode: genetically encodedimplementation constraint: context specific validationimplementation constraint: spectral hardware requirementoperating role: actuator
The evidence only establishes that lncRNAs are non-coding RNAs with reported roles in plant light-dependent biology. No practical implementation details are provided regarding expression systems, delivery methods, sequence features, cofactors, or assay formats.
The supplied evidence is limited to a review-level statement that available reports implicate lncRNAs in several light-dependent plant processes. It does not specify individual lncRNA sequences, molecular targets, effect sizes, wavelengths, construct designs, or direct validation as an engineered tool.
Validation
Cell-freeBacteriaMammalianMouseHumanTherapeuticIndep. Replication
Supporting Sources
Ranked Claims
Available reports indicate that lncRNAs have roles in photomorphogenesis, cotyledon greening, and photoperiod-regulated flowering.
In the lncRNA world, few reports are available, but they already indicate a role in the regulation of photomorphogenesis, cotyledon greening, and photoperiod-regulated flowering.
miRNAs can mediate several light-regulated processes.
In addition, miRNAs can mediate several light-regulated processes.
miRNAs can mediate several light-regulated processes.
In addition, miRNAs can mediate several light-regulated processes.
miRNAs can mediate several light-regulated processes.
In addition, miRNAs can mediate several light-regulated processes.
miRNAs can mediate several light-regulated processes.
In addition, miRNAs can mediate several light-regulated processes.
miRNAs can mediate several light-regulated processes.
In addition, miRNAs can mediate several light-regulated processes.
miRNAs can mediate several light-regulated processes.
In addition, miRNAs can mediate several light-regulated processes.
miRNAs can mediate several light-regulated processes.
In addition, miRNAs can mediate several light-regulated processes.
Light can affect MIRNA gene transcription, miRNA biogenesis, and RISC activity, thereby influencing miRNA accumulation and biological function.
Light can affect MIRNA gene transcription, miRNA biogenesis, and RNA-induced silencing complex (RISC) activity, thus controlling not only miRNA accumulation but also their biological function.
Light can affect MIRNA gene transcription, miRNA biogenesis, and RISC activity, thereby influencing miRNA accumulation and biological function.
Light can affect MIRNA gene transcription, miRNA biogenesis, and RNA-induced silencing complex (RISC) activity, thus controlling not only miRNA accumulation but also their biological function.
Light can affect MIRNA gene transcription, miRNA biogenesis, and RISC activity, thereby influencing miRNA accumulation and biological function.
Light can affect MIRNA gene transcription, miRNA biogenesis, and RNA-induced silencing complex (RISC) activity, thus controlling not only miRNA accumulation but also their biological function.
Light can affect MIRNA gene transcription, miRNA biogenesis, and RISC activity, thereby influencing miRNA accumulation and biological function.
Light can affect MIRNA gene transcription, miRNA biogenesis, and RNA-induced silencing complex (RISC) activity, thus controlling not only miRNA accumulation but also their biological function.
Light can affect MIRNA gene transcription, miRNA biogenesis, and RISC activity, thereby influencing miRNA accumulation and biological function.
Light can affect MIRNA gene transcription, miRNA biogenesis, and RNA-induced silencing complex (RISC) activity, thus controlling not only miRNA accumulation but also their biological function.
Light can affect MIRNA gene transcription, miRNA biogenesis, and RISC activity, thereby influencing miRNA accumulation and biological function.
Light can affect MIRNA gene transcription, miRNA biogenesis, and RNA-induced silencing complex (RISC) activity, thus controlling not only miRNA accumulation but also their biological function.
Light can affect MIRNA gene transcription, miRNA biogenesis, and RISC activity, thereby influencing miRNA accumulation and biological function.
Light can affect MIRNA gene transcription, miRNA biogenesis, and RNA-induced silencing complex (RISC) activity, thus controlling not only miRNA accumulation but also their biological function.
The review states that non-protein-coding RNAs are biologically relevant regulators of critical plant processes.
The biological relevance of non-protein coding RNAs in the regulation of critical plant processes has been firmly established in recent years.
The review states that non-protein-coding RNAs are biologically relevant regulators of critical plant processes.
The biological relevance of non-protein coding RNAs in the regulation of critical plant processes has been firmly established in recent years.
The review states that non-protein-coding RNAs are biologically relevant regulators of critical plant processes.
The biological relevance of non-protein coding RNAs in the regulation of critical plant processes has been firmly established in recent years.
The review states that non-protein-coding RNAs are biologically relevant regulators of critical plant processes.
The biological relevance of non-protein coding RNAs in the regulation of critical plant processes has been firmly established in recent years.
The review states that non-protein-coding RNAs are biologically relevant regulators of critical plant processes.
The biological relevance of non-protein coding RNAs in the regulation of critical plant processes has been firmly established in recent years.
The review states that non-protein-coding RNAs are biologically relevant regulators of critical plant processes.
The biological relevance of non-protein coding RNAs in the regulation of critical plant processes has been firmly established in recent years.
The review states that non-protein-coding RNAs are biologically relevant regulators of critical plant processes.
The biological relevance of non-protein coding RNAs in the regulation of critical plant processes has been firmly established in recent years.
Recent next-generation sequencing techniques expanded the recognized landscape of non-coding RNAs to include lncRNAs.
recent next-generation sequencing techniques have widened our view of the non-coding RNA world, which now includes long non-coding RNAs (lncRNAs)
Approval Evidence
1 source3 linked approval claimsfirst-pass slug long-non-coding-rna
the non-coding RNA world, which now includes long non-coding RNAs (lncRNAs)
Source:
process rolesupports
Available reports indicate that lncRNAs have roles in photomorphogenesis, cotyledon greening, and photoperiod-regulated flowering.
In the lncRNA world, few reports are available, but they already indicate a role in the regulation of photomorphogenesis, cotyledon greening, and photoperiod-regulated flowering.
Source:
review scope summarysupports
The review states that non-protein-coding RNAs are biologically relevant regulators of critical plant processes.
The biological relevance of non-protein coding RNAs in the regulation of critical plant processes has been firmly established in recent years.
Source:
technology enables scopesupports
Recent next-generation sequencing techniques expanded the recognized landscape of non-coding RNAs to include lncRNAs.
recent next-generation sequencing techniques have widened our view of the non-coding RNA world, which now includes long non-coding RNAs (lncRNAs)
Source:
Comparisons
Source-backed strengths
A review in Frontiers in Plant Science identifies lncRNAs as part of the non-coding RNA repertoire and reports roles in multiple plant light-regulated processes. This supports biological relevance across more than one developmental context, but does not provide quantitative performance metrics for a specific engineered construct.
Compared with phosphorothioate-caged antisense oligonucleotides
long non-coding RNA and phosphorothioate-caged antisense oligonucleotides address a similar problem space.
Shared frame: same top-level item type; same primary input modality: light
Compared with photo-sensitive circular gRNAs
long non-coding RNA and photo-sensitive circular gRNAs address a similar problem space.
Shared frame: same top-level item type; same primary input modality: light
Compared with RNA aptamer
long non-coding RNA and RNA aptamer address a similar problem space.
Shared frame: same top-level item type; same primary input modality: light
Ranked Citations
- 1.