Source 1review2020Current topics in developmental biology/Current Topics in Developmental Biology
Toolkit/omics
omics
Taxonomy: Technique Branch / Method. Workflows sit above the mechanism and technique branches rather than replacing them.
Summary
This review summarizes current understanding of signaling and morphogenesis during terminal patterning and discusses several open questions that can now be rigorously investigated using live imaging, omics, and optogenetic approaches.
Usefulness & Problems
Why this is useful
Omics is named as one of the approaches that can now be used to rigorously investigate open questions in terminal patterning. The abstract does not specify which omics modalities are intended.; rigorous investigation of open questions in terminal patterning
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Omics is named as one of the approaches that can now be used to rigorously investigate open questions in terminal patterning. The abstract does not specify which omics modalities are intended.
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rigorous investigation of open questions in terminal patterning
Problem solved
It is positioned as part of the modern toolkit for deeper investigation of terminal patterning biology.; provides a modern approach for interrogating terminal patterning questions
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It is positioned as part of the modern toolkit for deeper investigation of terminal patterning biology.
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provides a modern approach for interrogating terminal patterning questions
Problem links
provides a modern approach for interrogating terminal patterning questions
LiteratureIt is positioned as part of the modern toolkit for deeper investigation of terminal patterning biology.
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It is positioned as part of the modern toolkit for deeper investigation of terminal patterning biology.
Taxonomy & Function
Primary hierarchy
Technique Branch
Method: A concrete measurement method used to characterize an engineered system.
Mechanisms
No mechanism tags yet.
Techniques
Functional AssayTarget processes
signalingInput: Light
Implementation Constraints
cofactor dependency: cofactor requirement unknownencoding mode: genetically encodedimplementation constraint: context specific validationimplementation constraint: spectral hardware requirementoperating role: sensor
No specific omics platform, sample type, or analysis workflow is described in the provided evidence.
The abstract does not indicate that omics alone captures dynamic signaling or establishes causal control.
Validation
Cell-freeBacteriaMammalianMouseHumanTherapeuticIndep. Replication
Supporting Sources
Ranked Claims
Open questions in terminal patterning can now be rigorously investigated using live imaging, omics, and optogenetic approaches.
open questions that can now be rigorously investigated using live imaging, omics, and optogenetic approaches
The Drosophila terminal patterning system is a premier quantitative model because of its anatomical simplicity and amenability to increasingly sophisticated genetic perturbations.
The anatomical simplicity of the terminal patterning system and its amenability to a broad range of increasingly sophisticated genetic perturbations will continue to make it a premier quantitative model
Approval Evidence
1 source1 linked approval claimfirst-pass slug omics
This review summarizes current understanding of signaling and morphogenesis during terminal patterning and discusses several open questions that can now be rigorously investigated using live imaging, omics, and optogenetic approaches.
Source:
method applicabilitysupports
Open questions in terminal patterning can now be rigorously investigated using live imaging, omics, and optogenetic approaches.
open questions that can now be rigorously investigated using live imaging, omics, and optogenetic approaches
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Comparisons
Source-stated alternatives
The abstract contrasts omics with live imaging and optogenetic approaches as complementary ways to study the system.
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The abstract contrasts omics with live imaging and optogenetic approaches as complementary ways to study the system.
Source-backed strengths
presented as a rigorous investigative approach
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presented as a rigorous investigative approach
Compared with imaging
The abstract contrasts omics with live imaging and optogenetic approaches as complementary ways to study the system.
Shared frame: source-stated alternative in extracted literature
Strengths here: presented as a rigorous investigative approach.
Source:
The abstract contrasts omics with live imaging and optogenetic approaches as complementary ways to study the system.
Compared with imaging surveillance
The abstract contrasts omics with live imaging and optogenetic approaches as complementary ways to study the system.
Shared frame: source-stated alternative in extracted literature
Strengths here: presented as a rigorous investigative approach.
Source:
The abstract contrasts omics with live imaging and optogenetic approaches as complementary ways to study the system.
Compared with live imaging
The abstract contrasts omics with live imaging and optogenetic approaches as complementary ways to study the system.
Shared frame: source-stated alternative in extracted literature
Strengths here: presented as a rigorous investigative approach.
Source:
The abstract contrasts omics with live imaging and optogenetic approaches as complementary ways to study the system.
Compared with optogenetic
The abstract contrasts omics with live imaging and optogenetic approaches as complementary ways to study the system.
Shared frame: source-stated alternative in extracted literature
Strengths here: presented as a rigorous investigative approach.
Source:
The abstract contrasts omics with live imaging and optogenetic approaches as complementary ways to study the system.
Ranked Citations
- 1.