Source 1primary paper2015Scientific Reports
Toolkit/somatosensory evoked potentials
somatosensory evoked potentials
Also known as: SEP
Taxonomy: Technique Branch / Method. Workflows sit above the mechanism and technique branches rather than replacing them.
Summary
The source lead states that the paper used EEG/SEP readouts.
Usefulness & Problems
Why this is useful
Somatosensory evoked potentials were explicitly named as a readout in the anchor study. They fit the paper's focus on stimulation of human primary somatosensory cortex.; somatosensory response readout in human focused-ultrasound stimulation studies
Source:
Somatosensory evoked potentials were explicitly named as a readout in the anchor study. They fit the paper's focus on stimulation of human primary somatosensory cortex.
Source:
somatosensory response readout in human focused-ultrasound stimulation studies
Problem solved
It provides a somatosensory-system-relevant measurement for evaluating the reported stimulation effects.; provides a reported somatosensory electrophysiology readout for the stimulation paradigm
Source:
It provides a somatosensory-system-relevant measurement for evaluating the reported stimulation effects.
Source:
provides a reported somatosensory electrophysiology readout for the stimulation paradigm
Problem links
provides a reported somatosensory electrophysiology readout for the stimulation paradigm
LiteratureIt provides a somatosensory-system-relevant measurement for evaluating the reported stimulation effects.
Source:
It provides a somatosensory-system-relevant measurement for evaluating the reported stimulation effects.
Published Workflows
Objective: To noninvasively stimulate the human primary somatosensory cortex using image-guided transcranial focused ultrasound and assess responses with electrophysiological readouts.
Why it works: The provided source summary indicates that image guidance was used to target the cortical region and electrophysiological readouts were used to detect stimulation-related responses.
stimulation of human primary somatosensory cortexMRI/CT-guided targetingEEG readoutsomatosensory evoked potential readout
Stages
- 1.Image-guided targeting(functional_characterization)
The source summary explicitly states that MRI/CT guidance was used for targeting before electrophysiological readout.
Selection: MRI/CT-guided localization of the human primary somatosensory cortex for transcranial focused ultrasound application
- 2.Electrophysiological response assessment(confirmatory_validation)
The source summary explicitly identifies EEG and SEP as readouts used to assess the stimulation paradigm.
Selection: EEG and somatosensory evoked potential readouts after focused ultrasound stimulation
Taxonomy & Function
Primary hierarchy
Technique Branch
Method: A concrete measurement method used to characterize an engineered system.
Techniques
Functional AssayTarget processes
No target processes tagged yet.
Implementation Constraints
cofactor dependency: cofactor requirement unknownencoding mode: genetically encodedimplementation constraint: context specific validationimplementation constraint: payload burdenoperating role: sensor
The reported study used SEP as part of its electrophysiology readout stack. The payload does not provide additional acquisition details.; requires SEP measurement in the reported human stimulation setup
The supplied evidence does not establish whether SEP alone is sufficient for targeting, safety assessment, or mechanistic interpretation.; the provided evidence does not specify exact SEP changes or quantitative thresholds
Validation
Cell-freeBacteriaMammalianMouseHumanTherapeuticIndep. Replication
Supporting Sources
Ranked Claims
Image-guided transcranial focused ultrasound stimulates the human primary somatosensory cortex.
Image-Guided Transcranial Focused Ultrasound Stimulates Human Primary Somatosensory Cortex
The reported transcranial focused ultrasound setup used a 250 kHz pulsed transducer.
using MRI/CT-guided targeting, EEG/SEP readouts, and a 250 kHz pulsed transducer
transducer frequency 250 kHz
The study used EEG and somatosensory evoked potentials as readouts for image-guided transcranial focused ultrasound stimulation of human primary somatosensory cortex.
using MRI/CT-guided targeting, EEG/SEP readouts, and a 250 kHz pulsed transducer
Approval Evidence
1 source1 linked approval claimfirst-pass slug somatosensory-evoked-potentials
The source lead states that the paper used EEG/SEP readouts.
Source:
measurement setupsupports
The study used EEG and somatosensory evoked potentials as readouts for image-guided transcranial focused ultrasound stimulation of human primary somatosensory cortex.
using MRI/CT-guided targeting, EEG/SEP readouts, and a 250 kHz pulsed transducer
Source:
Comparisons
Source-stated alternatives
EEG is explicitly mentioned alongside SEP as another readout used in the study.
Source:
EEG is explicitly mentioned alongside SEP as another readout used in the study.
Source-backed strengths
explicitly linked to the somatosensory target domain of the study
Source:
explicitly linked to the somatosensory target domain of the study
Compared with Langendorff perfused heart electrical recordings
somatosensory evoked potentials and Langendorff perfused heart electrical recordings address a similar problem space.
Shared frame: same top-level item type
Strengths here: looks easier to implement in practice.
Compared with native green gel system
somatosensory evoked potentials and native green gel system address a similar problem space.
Shared frame: same top-level item type
Strengths here: looks easier to implement in practice.
somatosensory evoked potentials and sub-picosecond pump-probe analysis of bacteriorhodopsin pigments address a similar problem space.
Shared frame: same top-level item type
Strengths here: looks easier to implement in practice.
Ranked Citations
- 1.