Source 1review2020Cell and Tissue Research
Toolkit/Tracer-based magnetic resonance imaging
Tracer-based magnetic resonance imaging
Also known as: tracer-based MRI
Taxonomy: Technique Branch / Method. Workflows sit above the mechanism and technique branches rather than replacing them.
Summary
tracer-based magnetic resonance imaging ... can be used to visualize ... the interstitial system of the brain
Usefulness & Problems
Why this is useful
This modality is described as using MRI with tracers to visualize the interstitial system of the brain. The review includes it as a key CNS imaging approach.; visualizing the interstitial system of the brain; exploring mechanisms underlying CNS disease models; evaluating effects of drugs in neuroscience studies
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This modality is described as using MRI with tracers to visualize the interstitial system of the brain. The review includes it as a key CNS imaging approach.
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visualizing the interstitial system of the brain
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exploring mechanisms underlying CNS disease models
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evaluating effects of drugs in neuroscience studies
Problem solved
It addresses the need to visualize brain interstitial-system features in neuroscience and disease-model studies.; enables imaging of the brain interstitial system
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It addresses the need to visualize brain interstitial-system features in neuroscience and disease-model studies.
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enables imaging of the brain interstitial system
Problem links
enables imaging of the brain interstitial system
LiteratureIt addresses the need to visualize brain interstitial-system features in neuroscience and disease-model studies.
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It addresses the need to visualize brain interstitial-system features in neuroscience and disease-model studies.
Taxonomy & Function
Primary hierarchy
Technique Branch
Method: A concrete measurement method used to characterize an engineered system.
Techniques
Functional AssayTarget processes
No target processes tagged yet.
Input: Light
Implementation Constraints
cofactor dependency: cofactor requirement unknownencoding mode: genetically encodedimplementation constraint: context specific validationimplementation constraint: spectral hardware requirementoperating role: sensor
The abstract supports that MRI and tracer use are required. Specific tracers, acquisition settings, and analysis steps are not given in the supplied text.; requires MRI-based imaging with tracers
The abstract does not claim that this modality is used to visualize neuronal circuits or small molecules in brain tissue in the same way as the other named methods.
Validation
Cell-freeBacteriaMammalianMouseHumanTherapeuticIndep. Replication
Supporting Sources
Ranked Claims
These reviewed tools serve as powerful technical means to explore mechanisms underlying disease models and to evaluate drug effects in neuroscience.
CLARITY technology and optogenetics can be used to visualize neuronal circuits in whole-brain samples.
Tracer-based magnetic resonance imaging can be used to visualize the interstitial system of the brain.
The review covers MALDI time-of-flight mass spectrometry imaging, tracer-based MRI, CLARITY technology, and optogenetics as CNS study tools.
Approval Evidence
1 source3 linked approval claimsfirst-pass slug tracer-based-magnetic-resonance-imaging
tracer-based magnetic resonance imaging ... can be used to visualize ... the interstitial system of the brain
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application summarysupports
These reviewed tools serve as powerful technical means to explore mechanisms underlying disease models and to evaluate drug effects in neuroscience.
Source:
capability summarysupports
Tracer-based magnetic resonance imaging can be used to visualize the interstitial system of the brain.
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review scope summarysupports
The review covers MALDI time-of-flight mass spectrometry imaging, tracer-based MRI, CLARITY technology, and optogenetics as CNS study tools.
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Comparisons
Source-stated alternatives
The review contrasts this approach with MALDI mass spectrometry imaging, CLARITY technology, and optogenetics.
Source:
The review contrasts this approach with MALDI mass spectrometry imaging, CLARITY technology, and optogenetics.
Source-backed strengths
presented as a powerful technical means for neuroscience studies
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presented as a powerful technical means for neuroscience studies
Compared with CLARITY
The review contrasts this approach with MALDI mass spectrometry imaging, CLARITY technology, and optogenetics.
Shared frame: source-stated alternative in extracted literature
Strengths here: presented as a powerful technical means for neuroscience studies.
Source:
The review contrasts this approach with MALDI mass spectrometry imaging, CLARITY technology, and optogenetics.
Compared with CLARITY technology
The review contrasts this approach with MALDI mass spectrometry imaging, CLARITY technology, and optogenetics.
Shared frame: source-stated alternative in extracted literature
Strengths here: presented as a powerful technical means for neuroscience studies.
Source:
The review contrasts this approach with MALDI mass spectrometry imaging, CLARITY technology, and optogenetics.
Compared with imaging
The review contrasts this approach with MALDI mass spectrometry imaging, CLARITY technology, and optogenetics.
Shared frame: source-stated alternative in extracted literature
Strengths here: presented as a powerful technical means for neuroscience studies.
Source:
The review contrasts this approach with MALDI mass spectrometry imaging, CLARITY technology, and optogenetics.
Compared with imaging surveillance
The review contrasts this approach with MALDI mass spectrometry imaging, CLARITY technology, and optogenetics.
Shared frame: source-stated alternative in extracted literature
Strengths here: presented as a powerful technical means for neuroscience studies.
Source:
The review contrasts this approach with MALDI mass spectrometry imaging, CLARITY technology, and optogenetics.
Compared with mass spectrometry
The review contrasts this approach with MALDI mass spectrometry imaging, CLARITY technology, and optogenetics.
Shared frame: source-stated alternative in extracted literature
Strengths here: presented as a powerful technical means for neuroscience studies.
Source:
The review contrasts this approach with MALDI mass spectrometry imaging, CLARITY technology, and optogenetics.
Compared with optogenetic functional interrogation
The review contrasts this approach with MALDI mass spectrometry imaging, CLARITY technology, and optogenetics.
Shared frame: source-stated alternative in extracted literature
Strengths here: presented as a powerful technical means for neuroscience studies.
Source:
The review contrasts this approach with MALDI mass spectrometry imaging, CLARITY technology, and optogenetics.
Compared with optogenetic membrane potential perturbation
The review contrasts this approach with MALDI mass spectrometry imaging, CLARITY technology, and optogenetics.
Shared frame: source-stated alternative in extracted literature
Strengths here: presented as a powerful technical means for neuroscience studies.
Source:
The review contrasts this approach with MALDI mass spectrometry imaging, CLARITY technology, and optogenetics.
Ranked Citations
- 1.