Source 1review2014Epilepsia
Toolkit/two-photon guided whole-cell recording
two-photon guided whole-cell recording
Taxonomy: Technique Branch / Method. Workflows sit above the mechanism and technique branches rather than replacing them.
Summary
Two-photon guided whole-cell recording is an emerging electrophysiological assay method identified as combinable with the optogenetic toolbox. In the cited epilepsy context, it is positioned for recording from defined cells while optogenetic perturbations are used to probe circuit function.
Usefulness & Problems
Why this is useful
This method is useful because it links whole-cell electrophysiology with optical guidance and can be integrated with optogenetic manipulations. The cited source frames this combination as a way to gain insight into neuronal network organization and synchronization in epilepsy models.
Problem solved
It helps address the problem of functionally interrogating specific cells within epileptic networks while applying optogenetic control. The available evidence indicates this role in general terms, but does not provide a detailed protocol or a specific demonstrated neuron-targeting workflow.
Problem links
Need precise spatiotemporal control with light input
DerivedTwo-photon guided whole-cell recording is an emerging electrophysiological assay method described as combinable with the optogenetic toolbox. In the cited epilepsy context, it is used alongside optogenetic perturbation to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
Taxonomy & Function
Primary hierarchy
Technique Branch
Method: A concrete measurement method used to characterize an engineered system.
Mechanisms
combination with optogenetic photostimulationoptogenetic photostimulationtwo-photon optical guidancetwo-photon optical guidancewhole-cell patch-clamp recordingwhole-cell patch-clamp recordingTarget processes
No target processes tagged yet.
Input: Light
Implementation Constraints
cofactor dependency: cofactor requirement unknownencoding mode: genetically encodedimplementation constraint: context specific validationimplementation constraint: spectral hardware requirementoperating role: sensor
The method involves two-photon optical guidance and whole-cell patch-clamp recording, with possible combination with optogenetic photostimulation. The supplied evidence does not specify optical wavelengths, recording configuration details, animal models, expression systems, or construct design requirements.
The evidence is sparse and only states that the technique is emerging and combinable with optogenetics. No quantitative performance data, cell-type specificity metrics, preparation details, or independent validation studies are provided in the supplied evidence.
Validation
Cell-freeBacteriaMammalianMouseHumanTherapeuticIndep. Replication
Supporting Sources
Ranked Claims
Light-activated Gq protein-coupled opsins are described as a way to selectively activate astrocytes to explore the influence of gliotransmission on epileptic network function.
The influence of gliotransmission on epileptic network function is another topic of great interest that can be further explored by using light-activated Gq protein-coupled opsins for selective activation of astrocytes.
Light-activated Gq protein-coupled opsins are described as a way to selectively activate astrocytes to explore the influence of gliotransmission on epileptic network function.
The influence of gliotransmission on epileptic network function is another topic of great interest that can be further explored by using light-activated Gq protein-coupled opsins for selective activation of astrocytes.
Light-activated Gq protein-coupled opsins are described as a way to selectively activate astrocytes to explore the influence of gliotransmission on epileptic network function.
The influence of gliotransmission on epileptic network function is another topic of great interest that can be further explored by using light-activated Gq protein-coupled opsins for selective activation of astrocytes.
Light-activated Gq protein-coupled opsins are described as a way to selectively activate astrocytes to explore the influence of gliotransmission on epileptic network function.
The influence of gliotransmission on epileptic network function is another topic of great interest that can be further explored by using light-activated Gq protein-coupled opsins for selective activation of astrocytes.
Light-activated Gq protein-coupled opsins are described as a way to selectively activate astrocytes to explore the influence of gliotransmission on epileptic network function.
The influence of gliotransmission on epileptic network function is another topic of great interest that can be further explored by using light-activated Gq protein-coupled opsins for selective activation of astrocytes.
Light-activated Gq protein-coupled opsins are described as a way to selectively activate astrocytes to explore the influence of gliotransmission on epileptic network function.
The influence of gliotransmission on epileptic network function is another topic of great interest that can be further explored by using light-activated Gq protein-coupled opsins for selective activation of astrocytes.
Light-activated Gq protein-coupled opsins are described as a way to selectively activate astrocytes to explore the influence of gliotransmission on epileptic network function.
The influence of gliotransmission on epileptic network function is another topic of great interest that can be further explored by using light-activated Gq protein-coupled opsins for selective activation of astrocytes.
Light-activated Gq protein-coupled opsins are described as a way to selectively activate astrocytes to explore the influence of gliotransmission on epileptic network function.
The influence of gliotransmission on epileptic network function is another topic of great interest that can be further explored by using light-activated Gq protein-coupled opsins for selective activation of astrocytes.
Light-activated Gq protein-coupled opsins are described as a way to selectively activate astrocytes to explore the influence of gliotransmission on epileptic network function.
The influence of gliotransmission on epileptic network function is another topic of great interest that can be further explored by using light-activated Gq protein-coupled opsins for selective activation of astrocytes.
Light-activated Gq protein-coupled opsins are described as a way to selectively activate astrocytes to explore the influence of gliotransmission on epileptic network function.
The influence of gliotransmission on epileptic network function is another topic of great interest that can be further explored by using light-activated Gq protein-coupled opsins for selective activation of astrocytes.
Light-activated Gq protein-coupled opsins are described as a way to selectively activate astrocytes to explore the influence of gliotransmission on epileptic network function.
The influence of gliotransmission on epileptic network function is another topic of great interest that can be further explored by using light-activated Gq protein-coupled opsins for selective activation of astrocytes.
Light-activated Gq protein-coupled opsins are described as a way to selectively activate astrocytes to explore the influence of gliotransmission on epileptic network function.
The influence of gliotransmission on epileptic network function is another topic of great interest that can be further explored by using light-activated Gq protein-coupled opsins for selective activation of astrocytes.
Light-activated Gq protein-coupled opsins are described as a way to selectively activate astrocytes to explore the influence of gliotransmission on epileptic network function.
The influence of gliotransmission on epileptic network function is another topic of great interest that can be further explored by using light-activated Gq protein-coupled opsins for selective activation of astrocytes.
Light-activated Gq protein-coupled opsins are described as a way to selectively activate astrocytes to explore the influence of gliotransmission on epileptic network function.
The influence of gliotransmission on epileptic network function is another topic of great interest that can be further explored by using light-activated Gq protein-coupled opsins for selective activation of astrocytes.
Light-activated Gq protein-coupled opsins are described as a way to selectively activate astrocytes to explore the influence of gliotransmission on epileptic network function.
The influence of gliotransmission on epileptic network function is another topic of great interest that can be further explored by using light-activated Gq protein-coupled opsins for selective activation of astrocytes.
Light-activated Gq protein-coupled opsins are described as a way to selectively activate astrocytes to explore the influence of gliotransmission on epileptic network function.
The influence of gliotransmission on epileptic network function is another topic of great interest that can be further explored by using light-activated Gq protein-coupled opsins for selective activation of astrocytes.
Light-activated Gq protein-coupled opsins are described as a way to selectively activate astrocytes to explore the influence of gliotransmission on epileptic network function.
The influence of gliotransmission on epileptic network function is another topic of great interest that can be further explored by using light-activated Gq protein-coupled opsins for selective activation of astrocytes.
Light-activated Gq protein-coupled opsins are described as a way to selectively activate astrocytes to explore the influence of gliotransmission on epileptic network function.
The influence of gliotransmission on epileptic network function is another topic of great interest that can be further explored by using light-activated Gq protein-coupled opsins for selective activation of astrocytes.
Light-activated Gq protein-coupled opsins are described as a way to selectively activate astrocytes to explore the influence of gliotransmission on epileptic network function.
The influence of gliotransmission on epileptic network function is another topic of great interest that can be further explored by using light-activated Gq protein-coupled opsins for selective activation of astrocytes.
Light-activated Gq protein-coupled opsins are described as a way to selectively activate astrocytes to explore the influence of gliotransmission on epileptic network function.
The influence of gliotransmission on epileptic network function is another topic of great interest that can be further explored by using light-activated Gq protein-coupled opsins for selective activation of astrocytes.
Channelrhodopsin-2, halorhodopsin, and archaerhodopsin-3 are presented as potent optogenetic candidates for controlling neuronal firing in models of epilepsy and for providing insights into neuronal network organization and synchronization.
The versatility and the electrophysiologic characteristics of the light-sensitive ion-channels channelrhodopsin-2 (ChR2), halorhodopsin (NpHR), and the light-sensitive proton pump archaerhodopsin-3 (Arch) make these optogenetic tools potent candidates in controlling neuronal firing in models of epilepsy and in providing insights into the physiology and pathology of neuronal network organization and synchronization.
Channelrhodopsin-2, halorhodopsin, and archaerhodopsin-3 are presented as potent optogenetic candidates for controlling neuronal firing in models of epilepsy and for providing insights into neuronal network organization and synchronization.
The versatility and the electrophysiologic characteristics of the light-sensitive ion-channels channelrhodopsin-2 (ChR2), halorhodopsin (NpHR), and the light-sensitive proton pump archaerhodopsin-3 (Arch) make these optogenetic tools potent candidates in controlling neuronal firing in models of epilepsy and in providing insights into the physiology and pathology of neuronal network organization and synchronization.
Channelrhodopsin-2, halorhodopsin, and archaerhodopsin-3 are presented as potent optogenetic candidates for controlling neuronal firing in models of epilepsy and for providing insights into neuronal network organization and synchronization.
The versatility and the electrophysiologic characteristics of the light-sensitive ion-channels channelrhodopsin-2 (ChR2), halorhodopsin (NpHR), and the light-sensitive proton pump archaerhodopsin-3 (Arch) make these optogenetic tools potent candidates in controlling neuronal firing in models of epilepsy and in providing insights into the physiology and pathology of neuronal network organization and synchronization.
Channelrhodopsin-2, halorhodopsin, and archaerhodopsin-3 are presented as potent optogenetic candidates for controlling neuronal firing in models of epilepsy and for providing insights into neuronal network organization and synchronization.
The versatility and the electrophysiologic characteristics of the light-sensitive ion-channels channelrhodopsin-2 (ChR2), halorhodopsin (NpHR), and the light-sensitive proton pump archaerhodopsin-3 (Arch) make these optogenetic tools potent candidates in controlling neuronal firing in models of epilepsy and in providing insights into the physiology and pathology of neuronal network organization and synchronization.
Channelrhodopsin-2, halorhodopsin, and archaerhodopsin-3 are presented as potent optogenetic candidates for controlling neuronal firing in models of epilepsy and for providing insights into neuronal network organization and synchronization.
The versatility and the electrophysiologic characteristics of the light-sensitive ion-channels channelrhodopsin-2 (ChR2), halorhodopsin (NpHR), and the light-sensitive proton pump archaerhodopsin-3 (Arch) make these optogenetic tools potent candidates in controlling neuronal firing in models of epilepsy and in providing insights into the physiology and pathology of neuronal network organization and synchronization.
Channelrhodopsin-2, halorhodopsin, and archaerhodopsin-3 are presented as potent optogenetic candidates for controlling neuronal firing in models of epilepsy and for providing insights into neuronal network organization and synchronization.
The versatility and the electrophysiologic characteristics of the light-sensitive ion-channels channelrhodopsin-2 (ChR2), halorhodopsin (NpHR), and the light-sensitive proton pump archaerhodopsin-3 (Arch) make these optogenetic tools potent candidates in controlling neuronal firing in models of epilepsy and in providing insights into the physiology and pathology of neuronal network organization and synchronization.
Channelrhodopsin-2, halorhodopsin, and archaerhodopsin-3 are presented as potent optogenetic candidates for controlling neuronal firing in models of epilepsy and for providing insights into neuronal network organization and synchronization.
The versatility and the electrophysiologic characteristics of the light-sensitive ion-channels channelrhodopsin-2 (ChR2), halorhodopsin (NpHR), and the light-sensitive proton pump archaerhodopsin-3 (Arch) make these optogenetic tools potent candidates in controlling neuronal firing in models of epilepsy and in providing insights into the physiology and pathology of neuronal network organization and synchronization.
Channelrhodopsin-2, halorhodopsin, and archaerhodopsin-3 are presented as potent optogenetic candidates for controlling neuronal firing in models of epilepsy and for providing insights into neuronal network organization and synchronization.
The versatility and the electrophysiologic characteristics of the light-sensitive ion-channels channelrhodopsin-2 (ChR2), halorhodopsin (NpHR), and the light-sensitive proton pump archaerhodopsin-3 (Arch) make these optogenetic tools potent candidates in controlling neuronal firing in models of epilepsy and in providing insights into the physiology and pathology of neuronal network organization and synchronization.
Channelrhodopsin-2, halorhodopsin, and archaerhodopsin-3 are presented as potent optogenetic candidates for controlling neuronal firing in models of epilepsy and for providing insights into neuronal network organization and synchronization.
The versatility and the electrophysiologic characteristics of the light-sensitive ion-channels channelrhodopsin-2 (ChR2), halorhodopsin (NpHR), and the light-sensitive proton pump archaerhodopsin-3 (Arch) make these optogenetic tools potent candidates in controlling neuronal firing in models of epilepsy and in providing insights into the physiology and pathology of neuronal network organization and synchronization.
Channelrhodopsin-2, halorhodopsin, and archaerhodopsin-3 are presented as potent optogenetic candidates for controlling neuronal firing in models of epilepsy and for providing insights into neuronal network organization and synchronization.
The versatility and the electrophysiologic characteristics of the light-sensitive ion-channels channelrhodopsin-2 (ChR2), halorhodopsin (NpHR), and the light-sensitive proton pump archaerhodopsin-3 (Arch) make these optogenetic tools potent candidates in controlling neuronal firing in models of epilepsy and in providing insights into the physiology and pathology of neuronal network organization and synchronization.
Channelrhodopsin-2, halorhodopsin, and archaerhodopsin-3 are presented as potent optogenetic candidates for controlling neuronal firing in models of epilepsy and for providing insights into neuronal network organization and synchronization.
The versatility and the electrophysiologic characteristics of the light-sensitive ion-channels channelrhodopsin-2 (ChR2), halorhodopsin (NpHR), and the light-sensitive proton pump archaerhodopsin-3 (Arch) make these optogenetic tools potent candidates in controlling neuronal firing in models of epilepsy and in providing insights into the physiology and pathology of neuronal network organization and synchronization.
Channelrhodopsin-2, halorhodopsin, and archaerhodopsin-3 are presented as potent optogenetic candidates for controlling neuronal firing in models of epilepsy and for providing insights into neuronal network organization and synchronization.
The versatility and the electrophysiologic characteristics of the light-sensitive ion-channels channelrhodopsin-2 (ChR2), halorhodopsin (NpHR), and the light-sensitive proton pump archaerhodopsin-3 (Arch) make these optogenetic tools potent candidates in controlling neuronal firing in models of epilepsy and in providing insights into the physiology and pathology of neuronal network organization and synchronization.
Channelrhodopsin-2, halorhodopsin, and archaerhodopsin-3 are presented as potent optogenetic candidates for controlling neuronal firing in models of epilepsy and for providing insights into neuronal network organization and synchronization.
The versatility and the electrophysiologic characteristics of the light-sensitive ion-channels channelrhodopsin-2 (ChR2), halorhodopsin (NpHR), and the light-sensitive proton pump archaerhodopsin-3 (Arch) make these optogenetic tools potent candidates in controlling neuronal firing in models of epilepsy and in providing insights into the physiology and pathology of neuronal network organization and synchronization.
Channelrhodopsin-2, halorhodopsin, and archaerhodopsin-3 are presented as potent optogenetic candidates for controlling neuronal firing in models of epilepsy and for providing insights into neuronal network organization and synchronization.
The versatility and the electrophysiologic characteristics of the light-sensitive ion-channels channelrhodopsin-2 (ChR2), halorhodopsin (NpHR), and the light-sensitive proton pump archaerhodopsin-3 (Arch) make these optogenetic tools potent candidates in controlling neuronal firing in models of epilepsy and in providing insights into the physiology and pathology of neuronal network organization and synchronization.
Channelrhodopsin-2, halorhodopsin, and archaerhodopsin-3 are presented as potent optogenetic candidates for controlling neuronal firing in models of epilepsy and for providing insights into neuronal network organization and synchronization.
The versatility and the electrophysiologic characteristics of the light-sensitive ion-channels channelrhodopsin-2 (ChR2), halorhodopsin (NpHR), and the light-sensitive proton pump archaerhodopsin-3 (Arch) make these optogenetic tools potent candidates in controlling neuronal firing in models of epilepsy and in providing insights into the physiology and pathology of neuronal network organization and synchronization.
Channelrhodopsin-2, halorhodopsin, and archaerhodopsin-3 are presented as potent optogenetic candidates for controlling neuronal firing in models of epilepsy and for providing insights into neuronal network organization and synchronization.
The versatility and the electrophysiologic characteristics of the light-sensitive ion-channels channelrhodopsin-2 (ChR2), halorhodopsin (NpHR), and the light-sensitive proton pump archaerhodopsin-3 (Arch) make these optogenetic tools potent candidates in controlling neuronal firing in models of epilepsy and in providing insights into the physiology and pathology of neuronal network organization and synchronization.
Channelrhodopsin-2, halorhodopsin, and archaerhodopsin-3 are presented as potent optogenetic candidates for controlling neuronal firing in models of epilepsy and for providing insights into neuronal network organization and synchronization.
The versatility and the electrophysiologic characteristics of the light-sensitive ion-channels channelrhodopsin-2 (ChR2), halorhodopsin (NpHR), and the light-sensitive proton pump archaerhodopsin-3 (Arch) make these optogenetic tools potent candidates in controlling neuronal firing in models of epilepsy and in providing insights into the physiology and pathology of neuronal network organization and synchronization.
Channelrhodopsin-2, halorhodopsin, and archaerhodopsin-3 are presented as potent optogenetic candidates for controlling neuronal firing in models of epilepsy and for providing insights into neuronal network organization and synchronization.
The versatility and the electrophysiologic characteristics of the light-sensitive ion-channels channelrhodopsin-2 (ChR2), halorhodopsin (NpHR), and the light-sensitive proton pump archaerhodopsin-3 (Arch) make these optogenetic tools potent candidates in controlling neuronal firing in models of epilepsy and in providing insights into the physiology and pathology of neuronal network organization and synchronization.
Channelrhodopsin-2, halorhodopsin, and archaerhodopsin-3 are presented as potent optogenetic candidates for controlling neuronal firing in models of epilepsy and for providing insights into neuronal network organization and synchronization.
The versatility and the electrophysiologic characteristics of the light-sensitive ion-channels channelrhodopsin-2 (ChR2), halorhodopsin (NpHR), and the light-sensitive proton pump archaerhodopsin-3 (Arch) make these optogenetic tools potent candidates in controlling neuronal firing in models of epilepsy and in providing insights into the physiology and pathology of neuronal network organization and synchronization.
Channelrhodopsin-2, halorhodopsin, and archaerhodopsin-3 are presented as potent optogenetic candidates for controlling neuronal firing in models of epilepsy and for providing insights into neuronal network organization and synchronization.
The versatility and the electrophysiologic characteristics of the light-sensitive ion-channels channelrhodopsin-2 (ChR2), halorhodopsin (NpHR), and the light-sensitive proton pump archaerhodopsin-3 (Arch) make these optogenetic tools potent candidates in controlling neuronal firing in models of epilepsy and in providing insights into the physiology and pathology of neuronal network organization and synchronization.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
Optogenetic tools allow rapid and reversible suppression of epileptic EEG activity upon photoactivation.
Finally, optogenetic tools allow rapid and reversible suppression of epileptic electroencephalography (EEG) activity upon photoactivation.
Optogenetic tools allow rapid and reversible suppression of epileptic EEG activity upon photoactivation.
Finally, optogenetic tools allow rapid and reversible suppression of epileptic electroencephalography (EEG) activity upon photoactivation.
Optogenetic tools allow rapid and reversible suppression of epileptic EEG activity upon photoactivation.
Finally, optogenetic tools allow rapid and reversible suppression of epileptic electroencephalography (EEG) activity upon photoactivation.
Optogenetic tools allow rapid and reversible suppression of epileptic EEG activity upon photoactivation.
Finally, optogenetic tools allow rapid and reversible suppression of epileptic electroencephalography (EEG) activity upon photoactivation.
Optogenetic tools allow rapid and reversible suppression of epileptic EEG activity upon photoactivation.
Finally, optogenetic tools allow rapid and reversible suppression of epileptic electroencephalography (EEG) activity upon photoactivation.
Optogenetic tools allow rapid and reversible suppression of epileptic EEG activity upon photoactivation.
Finally, optogenetic tools allow rapid and reversible suppression of epileptic electroencephalography (EEG) activity upon photoactivation.
Optogenetic tools allow rapid and reversible suppression of epileptic EEG activity upon photoactivation.
Finally, optogenetic tools allow rapid and reversible suppression of epileptic electroencephalography (EEG) activity upon photoactivation.
Optogenetic tools allow rapid and reversible suppression of epileptic EEG activity upon photoactivation.
Finally, optogenetic tools allow rapid and reversible suppression of epileptic electroencephalography (EEG) activity upon photoactivation.
Optogenetic tools allow rapid and reversible suppression of epileptic EEG activity upon photoactivation.
Finally, optogenetic tools allow rapid and reversible suppression of epileptic electroencephalography (EEG) activity upon photoactivation.
Optogenetic tools allow rapid and reversible suppression of epileptic EEG activity upon photoactivation.
Finally, optogenetic tools allow rapid and reversible suppression of epileptic electroencephalography (EEG) activity upon photoactivation.
Optogenetic tools allow rapid and reversible suppression of epileptic EEG activity upon photoactivation.
Finally, optogenetic tools allow rapid and reversible suppression of epileptic electroencephalography (EEG) activity upon photoactivation.
Optogenetic tools allow rapid and reversible suppression of epileptic EEG activity upon photoactivation.
Finally, optogenetic tools allow rapid and reversible suppression of epileptic electroencephalography (EEG) activity upon photoactivation.
Optogenetic tools allow rapid and reversible suppression of epileptic EEG activity upon photoactivation.
Finally, optogenetic tools allow rapid and reversible suppression of epileptic electroencephalography (EEG) activity upon photoactivation.
Optogenetic tools allow rapid and reversible suppression of epileptic EEG activity upon photoactivation.
Finally, optogenetic tools allow rapid and reversible suppression of epileptic electroencephalography (EEG) activity upon photoactivation.
Optogenetic tools allow rapid and reversible suppression of epileptic EEG activity upon photoactivation.
Finally, optogenetic tools allow rapid and reversible suppression of epileptic electroencephalography (EEG) activity upon photoactivation.
Optogenetic tools allow rapid and reversible suppression of epileptic EEG activity upon photoactivation.
Finally, optogenetic tools allow rapid and reversible suppression of epileptic electroencephalography (EEG) activity upon photoactivation.
Optogenetic tools allow rapid and reversible suppression of epileptic EEG activity upon photoactivation.
Finally, optogenetic tools allow rapid and reversible suppression of epileptic electroencephalography (EEG) activity upon photoactivation.
Optogenetic tools allow rapid and reversible suppression of epileptic EEG activity upon photoactivation.
Finally, optogenetic tools allow rapid and reversible suppression of epileptic electroencephalography (EEG) activity upon photoactivation.
Optogenetic tools allow rapid and reversible suppression of epileptic EEG activity upon photoactivation.
Finally, optogenetic tools allow rapid and reversible suppression of epileptic electroencephalography (EEG) activity upon photoactivation.
Optogenetic tools allow rapid and reversible suppression of epileptic EEG activity upon photoactivation.
Finally, optogenetic tools allow rapid and reversible suppression of epileptic electroencephalography (EEG) activity upon photoactivation.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, including interneuron subclasses, to study activity patterns in distinct brain states and dissect roles in synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, or subclasses of interneurons, to study their activity patterns in distinct brain-states in vivo and to dissect their role in generation of synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, including interneuron subclasses, to study activity patterns in distinct brain states and dissect roles in synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, or subclasses of interneurons, to study their activity patterns in distinct brain-states in vivo and to dissect their role in generation of synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, including interneuron subclasses, to study activity patterns in distinct brain states and dissect roles in synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, or subclasses of interneurons, to study their activity patterns in distinct brain-states in vivo and to dissect their role in generation of synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, including interneuron subclasses, to study activity patterns in distinct brain states and dissect roles in synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, or subclasses of interneurons, to study their activity patterns in distinct brain-states in vivo and to dissect their role in generation of synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, including interneuron subclasses, to study activity patterns in distinct brain states and dissect roles in synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, or subclasses of interneurons, to study their activity patterns in distinct brain-states in vivo and to dissect their role in generation of synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, including interneuron subclasses, to study activity patterns in distinct brain states and dissect roles in synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, or subclasses of interneurons, to study their activity patterns in distinct brain-states in vivo and to dissect their role in generation of synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, including interneuron subclasses, to study activity patterns in distinct brain states and dissect roles in synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, or subclasses of interneurons, to study their activity patterns in distinct brain-states in vivo and to dissect their role in generation of synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, including interneuron subclasses, to study activity patterns in distinct brain states and dissect roles in synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, or subclasses of interneurons, to study their activity patterns in distinct brain-states in vivo and to dissect their role in generation of synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, including interneuron subclasses, to study activity patterns in distinct brain states and dissect roles in synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, or subclasses of interneurons, to study their activity patterns in distinct brain-states in vivo and to dissect their role in generation of synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, including interneuron subclasses, to study activity patterns in distinct brain states and dissect roles in synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, or subclasses of interneurons, to study their activity patterns in distinct brain-states in vivo and to dissect their role in generation of synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, including interneuron subclasses, to study activity patterns in distinct brain states and dissect roles in synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, or subclasses of interneurons, to study their activity patterns in distinct brain-states in vivo and to dissect their role in generation of synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, including interneuron subclasses, to study activity patterns in distinct brain states and dissect roles in synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, or subclasses of interneurons, to study their activity patterns in distinct brain-states in vivo and to dissect their role in generation of synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, including interneuron subclasses, to study activity patterns in distinct brain states and dissect roles in synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, or subclasses of interneurons, to study their activity patterns in distinct brain-states in vivo and to dissect their role in generation of synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, including interneuron subclasses, to study activity patterns in distinct brain states and dissect roles in synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, or subclasses of interneurons, to study their activity patterns in distinct brain-states in vivo and to dissect their role in generation of synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, including interneuron subclasses, to study activity patterns in distinct brain states and dissect roles in synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, or subclasses of interneurons, to study their activity patterns in distinct brain-states in vivo and to dissect their role in generation of synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, including interneuron subclasses, to study activity patterns in distinct brain states and dissect roles in synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, or subclasses of interneurons, to study their activity patterns in distinct brain-states in vivo and to dissect their role in generation of synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, including interneuron subclasses, to study activity patterns in distinct brain states and dissect roles in synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, or subclasses of interneurons, to study their activity patterns in distinct brain-states in vivo and to dissect their role in generation of synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, including interneuron subclasses, to study activity patterns in distinct brain states and dissect roles in synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, or subclasses of interneurons, to study their activity patterns in distinct brain-states in vivo and to dissect their role in generation of synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, including interneuron subclasses, to study activity patterns in distinct brain states and dissect roles in synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, or subclasses of interneurons, to study their activity patterns in distinct brain-states in vivo and to dissect their role in generation of synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, including interneuron subclasses, to study activity patterns in distinct brain states and dissect roles in synchrony and seizures.
Opsins allow selective activation of excitatory neurons and inhibitory interneurons, or subclasses of interneurons, to study their activity patterns in distinct brain-states in vivo and to dissect their role in generation of synchrony and seizures.
Approval Evidence
1 source1 linked approval claimfirst-pass slug two-photon-guided-whole-cell-recording
The abstract names two-photon guided whole-cell recording as an emerging technique that can be combined with the optogenetic toolbox.
Source:
combinatorial method usesupports
The optogenetic toolbox can be combined with juxtacellular recording and two-photon guided whole-cell recording to help identify specific cortical and hippocampal neuron subtypes altered in epileptic networks.
The ever-growing optogenetic toolbox can also be combined with emerging techniques that have greatly expanded our ability to record specific subtypes of cortical and hippocampal neurons in awake behaving animals such as juxtacellular recording and two-photon guided whole-cell recording, to identify the specific subtypes of neurons that are altered in epileptic networks.
Source:
Comparisons
Source-backed strengths
A key strength is that the method is explicitly described as compatible with the optogenetic toolbox, enabling combined recording and light-based perturbation. The source also situates this combined approach within epilepsy research aimed at understanding altered network function and synchronization.
Compared with native green gel system
two-photon guided whole-cell recording and native green gel system address a similar problem space.
Shared frame: same top-level item type; same primary input modality: light
Compared with open-source microplate reader
two-photon guided whole-cell recording and open-source microplate reader address a similar problem space.
Shared frame: same top-level item type; same primary input modality: light
Compared with plant transcriptome profiling
two-photon guided whole-cell recording and plant transcriptome profiling address a similar problem space.
Shared frame: same top-level item type; same primary input modality: light
Ranked Citations
- 1.