The Arabidopsis thaliana phototropin 1 LOV2 domain is a blue-light-sensing protein domain from phototropin 1 whose dark-adapted crystal structure has been determined. In this state, the domain is dimeric and contains an N-terminal A'α helix and a C-terminal Jα helix that contribute to coiled-coil-mediated dimerization.
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Mechanism Concept
dimerization
A mechanism-level grouping derived from the current toolkit evidence. Current coverage includes 0 architectures and 2 components. Across those tools, the main enabled capabilities are recombination, selection, and transcription. Representative components include GntR and phototropin 1 LOV2 domain.
2 total items0 architectures2 components
Main enabled capabilities: recombination, selection, transcription.
Components
2 of 2GntR is a gluconate-responsive transcriptional repressor from Escherichia coli that has been repurposed as a protein domain for synthetic gene-control switches. Reported designs use GntR to construct gluconate-regulated transcriptional systems in mammalian cells, including rewired OFF/ON transcriptional architectures and a split transcriptional activator.