CRISPR-Cas technology comprises CRISPR-associated effector proteins that recognize specific DNA or RNA sequences and cleave them. In the cited review, it is presented primarily as a platform for rapid pathogen nucleic acid detection that leverages Cas trans-cleavage activity together with signal amplification and signal transformation strategies.
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Mechanism Concept
trans-cleavage
A mechanism-level grouping derived from the current toolkit evidence. Current coverage includes 1 architecture and 0 components. Across those tools, the main enabled capabilities are diagnostic and editing.
1 total items1 architectures0 components
Main enabled capabilities: diagnostic, editing.